Evidence map›Paper›PMID 30453945›Full record

ArticleBMC infectious diseases2018

Evaluation of Senegal's prevention of mother to child transmission of HIV (PMTCT) program data for HIV surveillance.

Ousmane Diouf, Astou Gueye-Gaye, Moussa Sarr, Abdou Salam Mbengue, Christopher S Murrill, Jacob Dee, Papa Ousmane Diaw, Ndeye Fatou Ngom-Faye, Pape Amadou Niang Diallo, Carlos Suarez and 4 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ousmane DioufLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Astou Gueye-GayeLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Moussa SarrWestat, 1600 Research Blvd, WB 258, Rockville, MD, 20850, USA. moussasarr@westat.com.ORCID http://orcid.org/0000-0003-2372-6632
Abdou Salam MbengueLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Christopher S MurrillCenters for Disease Control and Prevention, 1600 Clifton Road, Atlanta, USA.
Jacob DeeCenters for Disease Control and Prevention, 1600 Clifton Road, Atlanta, USA.
Papa Ousmane DiawLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Ndeye Fatou Ngom-FayeDivision pour la Lutte Contre Le SIDA et les ISTs (DLSI), Dakar, Senegal.
Pape Amadou Niang DialloConseils National pour la Lutte Contre le SIDA (CNLS), Dakar, Senegal.
Carlos SuarezWestat, 1600 Research Blvd, WB 258, Rockville, MD, 20850, USA.
Massaer GueyeLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Aminata MboupLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Coumba Toure-KaneLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.
Souleymane MboupLaboratory of Bacteriology and Virology of Aristide Le Dantec University Hospital, Dakar, Senegal.

Funding

STRENGTHENING HIV STRATEGIC INFORMATION ACTIVITIES IN THE REPUBLIC OF SENEGAL UNDU2GPS002760 · PS · CHEIKH ANTA DIOP UNIVERSITY · PI MBOUP, SOULEYMANE · 2010 to 2014
$1.6M
Center for Global Health 5U2GPS002760NCHHSTP CDC HHS U2G PS002760
6 · The paper itself

Abstract

backgroundWith the expansion of Prevention of Mother to Child Transmission (PMTCT) services in Senegal, there is growing interest in using PMTCT program data in lieu of conducting unlinked anonymous testing (UAT)-based ANC Sentinel Surveillance. For this reason, an evaluation was conducted in 2011-2012 to identify the gaps that need to be addressed while transitioning to using PMTCT program data for surveillance.

methodsWe conducted analyses to assess HIV prevalence rates and agreements between Sentinel Surveillance and PMTCT HIV test results. Also, a data quality assessment of the PMTCT program registers and data was conducted during the Sentinel Surveillance period (December 2011 to March 2012) and 3 months prior. Finally, we also assessed selection bias, which was the percentage difference from the HIV prevalence among all women enrolled in the antenatal clinic and the HIV prevalence among women who accepted PMTCT HIV testing.

resultsThe median site HIV prevalence using routine PMTCT HIV testing data was 1.1% (IQR: 1.0) while the median site prevalence from the UAT HIV Sentinel Surveillance data was at 1.0% (IQR: 1.6). The Positive per cent agreement (PPA) of the PMTCT HIV test results compared to those of the Sentinel Surveillance was 85.1% (95% CI 77.2-90.7%), and the percent-negative agreement (PNA) was 99.9% (95% CI 99.8-99.9%). The overall HIV prevalence according to UAT was the same as that found for women accepting a PMTCT HIV test and those who refused, with percent bias at 0.00%. For several key PMTCT variables, including "HIV test offered" (85.2%), "HIV test acceptance" (78.0%), or "HIV test done" (58.8%), the proportion of records in registers with combined complete and valid data was below the WHO benchmark of 90%.

conclusionsThe PPA of 85.1 was below the WHO benchmarks of 96.6%, while the combined data validity and completeness rates was below the WHO benchmark of 90% for many key PMTCT variables. These results suggested that Senegal will need to reinforce the quality of onsite HIV testing and improve program data collection practices in preparation for using PMTCT data for surveillance purposes.

Indexed as

Infectious Disease Transmission, VerticalPrenatal CareAdolescentAdultAmbulatory Care FacilitiesChildFemaleHIVHIV InfectionsHumansInfant, NewbornMiddle AgedPregnancyPregnancy Complications, InfectiousPrevalenceProgram EvaluationAntenatal clinicHIVHIV surveillancePrevention of mother-to-child transmissionSenegalSentinel surveillance

Identifiers

PMID30453945
PMCPMC6245718

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.