Evidence map›Paper›PMID 30453806›Full record

ArticleThe Journal of international medical research2018

Congenital tuberculosis after in vitro fertilization: suggestion for tuberculosis tests in infertile women in developing countries.

Xiaoling Zhang, Ren Zhuxiao, Fang Xu, Qi Zhang, Haoming Yang, Liang Chen, Fenghua Liu, Jie Yang

Abstract readCase ReportsTwin Study
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Female Genital Tuberculosis.Open forum infectious diseases · 2022
    Review
  5. Article
  6. Association ofFrontiers in public health · 2022
    Article
  7. Article
  8. Tuberculosis in Pregnancy.Obstetrics and gynecology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoling Zhang1 Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Ren Zhuxiao1 Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Fang Xu1 Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Qi Zhang2 Department of Clinical Genetic center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Haoming Yang1 Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Liang Chen3 Centre for Tuberculosis Control of Guangdong Province, Guangdong, 510630, China.
Fenghua Liu4 Department of Assisted Reproductive Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.
Jie Yang1 Department of Neonatology, Guangdong Women and Children Hospital, Guangzhou, Guangdong, 510010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital tuberculosis (CTB) after in vitro fertilization (IVF) is a major new problem in developing countries. Only 16 cases of CTB after IVF have been reported, and no tuberculosis (TB) tests were performed before IVF in these cases. However, on the basis of data in the literature and from the World Health Organization, the incidence of CTB has been substantially underestimated. We describe two cases of CTB after IVF in detail in our center and provide new insight into the important issue of controlling TB vertical transmission in developing countries. Performing an early diagnosis of CTB, mostly based on evidence of maternal infection and a high index of clinical suspicion, is a challenge. However, most mothers have no symptoms of TB infection during prepartum, and infertility may be the only symptom. Infertility caused by genital TB is common in countries with a high TB burden, and IVF is considered to be an effective treatment to improve their fertility. Therefore, this may lead to more CTB cases without thorough TB tests before IVF. We suggest that thorough TB tests should be conducted in infertile women before IVF to prevent CTB.

Indexed as

Infectious Disease Transmission, VerticalDiseases in TwinsFemaleFertilization in VitroHumansInfant, NewbornInfertility, FemaleTuberculin TestTuberculosisTuberculosis, Female Genitalanti-tuberculosis therapyCongenital tuberculosisinfertilityin vitro fertilizationtwinsvertical transmission

Identifiers

PMID30453806
PMCPMC6300949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.