ArticleJournal of clinical medicine2018
Predictors of Exercise Capacity in Patients with Hypertrophic Obstructive Cardiomyopathy.
Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Sex Differences in Exercise Capacity and Outcomes Following Outpatient Cardiac Rehabilitation.Journal of the American Heart Association · 2026Article
- Gender-related differences in left atrial strain mechanics and exercise capacity in hypertrophic cardiomyopathy: a propensity-score matched study from the Cleveland Clinic.Cardiovascular diagnosis and therapy · 2024Article
- Clinical course of adults with co-occurring hypertrophic cardiomyopathy and hypertension: A scoping review.American heart journal plus : cardiology research and practice · 2024Article
- Predictors of Changes in Peak Oxygen Uptake After Outpatient Cardiac Rehabilitation: Importance of Cardiac Rehabilitation Attendance.Mayo Clinic proceedings. Innovations, quality & outcomes · 2022Article
- Article
- Hypertrophic cardiomyopathies requiring more monitoring for less atrial fibrillation-related complications: a clustering analysis based on the French registry on hypertrophic cardiomyopathy (REMY).Clinical research in cardiology : official journal of the German Cardiac Society · 2022Observational
- Cardiopulmonary Exercise Test in Patients with Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Review
- Clinical and Rehabilitative Predictors of Peak Oxygen Uptake Following Cardiac Transplantation.Journal of clinical medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Hypertrophic obstructive cardiomyopathy (HOCM) patients exhibit compromised peak exercise capacity (VO₂peak). Importantly, severely reduced VO₂peak is directly related to increased morbidity and mortality in these patients. Therefore, we sought to determine clinical predictors of VO₂peak in HOCM patients. HOCM patients who performed symptom-limited cardiopulmonary exercise testing between 1995 and 2016 were included for analysis. Peak VO₂ was reported as absolute peak VO₂, indexed to body weight and analyzed as quartiles, with quartile 1 representing the lowest VO₂peak. Step-wise regression models using demographic features and clinical and physiologic characteristics were created to determine predictors of HOCM patients with the lowest VO₂peak. We included 1177 HOCM patients (age: 53 ± 14 years; BMI: 24 ± 12 kg/m²) with a VO₂peak of 18.0 ± 5.6 mL/kg/min. Significant univariate predictors of the lowest VO₂peak included age, female sex, New York Health Association (NYHA) class, BMI, left atrial volume index, E/e', E/A, hemoglobin, N-terminal pro b-type natriuretic peptide (NT-proBNP), and a history of diabetes, hypertension, stroke, atrial fibrillation, or coronary artery disease. Independent predictors of the lowest VO₂peak included age (OR, CI: 1.03, 1.02⁻1.06;
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