Evidence map›Paper›PMID 30453670›Full record

ReviewInternational journal of molecular sciences2018

Protein Structural Dynamics of Wild-Type and Mutant Homodimeric Hemoglobin Studied by Time-Resolved X-Ray Solution Scattering.

Cheolhee Yang, Minseo Choi, Jong Goo Kim, Hanui Kim, Srinivasan Muniyappan, Shunsuke Nozawa, Shin-Ichi Adachi, Robert Henning, Irina Kosheleva, Hyotcherl Ihee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Structural Dynamics of CInternational journal of molecular sciences · 2021
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Cheolhee YangDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. eangel04@gmail.com.ORCID 0000-0002-4472-9982
Minseo ChoiDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. atlady05@gmail.com.
Jong Goo KimDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. 8808kjk@gmail.com.
Hanui KimDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. haneihanei92@gmail.com.
Srinivasan MuniyappanDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. smuniappan@gmail.com.
Shunsuke NozawaInstitute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan. noz@post.kek.jp.
Shin-Ichi AdachiInstitute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan. shinichi.adachi@kek.jp.
Robert HenningCenter for Advanced Radiation Sources, The University of Chicago, Chicago, IL 60637, USA. henning@cars.uchicago.edu.
Irina KoshelevaCenter for Advanced Radiation Sources, The University of Chicago, Chicago, IL 60637, USA. ikoshelev@cars.uchicago.edu.
Hyotcherl IheeDepartment of Chemistry and KI for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea. hyotcherl.ihee@kaist.ac.kr.ORCID 0000-0003-0397-5965
Korea Advanced Institute of Science and Technology · KRHigh Energy Accelerator Research Organization · JPUniversity of Chicago · US

Funding

X-RAY STUDY OF HORMONE-RECEPTOR AND PROTEIN-ANTIBODY COMPLEXESP41RR007707 · NCRR · UNIVERSITY OF CHICAGO · PI YANG, XIANGZHONG · 2002 to 2011
$17.3M
BioCARS: A Synchrotron Structure Biology ResourceR24GM111072 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 2013 to 2016
$2.3M
Institute for Basic Science IBS-R004NCRR NIH HHS P41 RR007707NIGMS NIH HHS R24 GM111072
6 · The paper itself

Abstract

The quaternary transition between the relaxed (R) and tense (T) states of heme-binding proteins is a textbook example for the allosteric structural transition. Homodimeric hemoglobin (HbI) from

Indexed as

Protein MultimerizationScattering, RadiationAnimalsHemoglobinsHumansMutant ProteinsTime FactorsX-RaysHemoglobinsMutant Proteinsallosteryhomodimeric hemoglobinmolecular cooperativityprotein dynamicstime-resolved X-ray solution scattering

Identifiers

PMID30453670
PMCPMC6274816
OpenAlexW2901796447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.