Evidence map›Paper›PMID 30453624›Full record

ArticleInternational journal of molecular sciences2018

Genome-Wide Transcriptional and Functional Analysis of Human T Lymphocytes Treated with Benzo[

Marie Liamin, Hélène Le Mentec, Bertrand Evrard, Laurence Huc, Frédéric Chalmel, Elisa Boutet-Robinet, Eric Le Ferrec, Lydie Sparfel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. The Role of GPR15 Function in Blood and Vasculature.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marie LiaminInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. marie.liamin@univ-rennes1.fr.
Hélène Le MentecInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. helene.le-mentec@univ-rennes1.fr.
Bertrand EvrardInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. bertrand.evrard@inserm.fr.
Laurence HucToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP-Purpan, UPS, 31027 Toulouse, France. laurence.huc@inra.fr.
Frédéric ChalmelInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. frederic.chalmel@univ-rennes1.fr.
Elisa Boutet-RobinetToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP-Purpan, UPS, 31027 Toulouse, France. elisa.boutet@univ-tlse3.fr.ORCID 0000-0002-5223-4568
Eric Le FerrecInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. eric.leferrec@univ-rennes1.fr.
Lydie SparfelInstitut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé, Environnement et Travail (IRSET-INSERM UMR 1085), 35000 Rennes, France. lydie.sparfel@univ-rennes1.fr.ORCID 0000-0002-4877-7017
Centre National de la Recherche Scientifique · FRInserm · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

French National Research Program for Environmental and Occupational Health of ANSES with the support of the Cancer TMOI of the French National Alliance for Life and Health Sciences (AVIESAN) 2014/1/052
6 · The paper itself

Abstract

Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental contaminants, known to affect T lymphocytes. However, the molecular targets and pathways involved in their immunotoxic effects in human T lymphocytes remain unknown. Here, we analyzed the gene expression profile of primary human T lymphocytes treated with the prototypical PAH, benzo[

Indexed as

Genome, HumanBenzo(a)pyreneChemotaxisGene Expression ProfilingGene Expression RegulationHumansInterferonsReceptors, Aryl HydrocarbonReproducibility of ResultsSignal TransductionT-LymphocytesTranscription, GeneticTransendothelial and Transepithelial MigrationBenzo(a)pyreneInterferonsReceptors, Aryl Hydrocarbonbenzo[α]pyreneimmunotoxicitymicroarraysmigrationT lymphocytes

Identifiers

PMID30453624
PMCPMC6274903
OpenAlexW2900836142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.