ArticlePlants (Basel, Switzerland)2018
Wheat ATI CM3, CM16 and 0.28 Allergens Produced in
Article in Plants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- From Peptide to Protein: Development of Conversion Factors for the Quantification of Gluten Using Targeted Mass Spectrometry.Journal of agricultural and food chemistry · 2025Article
- Does sourdough bread provide clinically relevant health benefits?Frontiers in nutrition · 2023Review
- Xylanase Inhibitors: Defense Players in Plant Immunity with Implications in Agro-Industrial Processing.International journal of molecular sciences · 2022Review
- Wheat Amylase Trypsin Inhibitors Aggravate Intestinal Inflammation Associated with Celiac Disease Mediated by Gliadin in BALB/c Mice.Foods (Basel, Switzerland) · 2022Article
- Structure, Function and Protein Engineering of Cereal-Type Inhibitors Acting on Amylolytic Enzymes.Frontiers in molecular biosciences · 2022Review
- Wheat ATIs: Characteristics and Role in Human Disease.Frontiers in nutrition · 2021Review
- Reduction of Allergenic Potential in Bread Wheat RNAi Transgenic Lines Silenced forInternational journal of molecular sciences · 2020Article
- Article
- Purification and Functional Characterization of the Chloroform/Methanol-Soluble Protein 3 (CM3) FromFrontiers in nutrition · 2020Article
- A New Approach of Extraction of α-Amylase/trypsin Inhibitors from Wheat (Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although wheat is a staple food for most of the human population, some of its components trigger adverse reactions. Among wheat components, the alpha-amylase/trypsin inhibitors (ATI) are important triggers of several allergies and activators of innate immunity. ATI are a group of exogenous protease inhibitors and include several polypeptides. The three ATI polypeptides named CM3, CM16 and 0.28 are considered major allergens, and might also play a role in other common wheat-related pathologies, such as Non Celiac Wheat Sensitivity and even Celiac Disease. On this basis, we pointed to obtain high amounts of them in purity and to evaluate their allergenicity potential. We thus isolated the mRNA corresponding to the three ATI genes CM3, CM16 and 0.28 from 28 days post-anthesis wheat kernels and the corresponding cDNAs were used for heterologous expression in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.