Evidence map›Paper›PMID 30453579›Full record

ArticleMolecules (Basel, Switzerland)2018

Natalenamides A⁻C, Cyclic Tripeptides from the Termite-Associated

Seoung Rak Lee, Dahae Lee, Jae Sik Yu, René Benndorf, Sullim Lee, Dong-Soo Lee, Jungmoo Huh, Z Wilhelm de Beer, Yong Ho Kim, Christine Beemelmanns and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Seoung Rak LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. davidseoungrak@gmail.com.
Dahae LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. pjsldh@naver.com.
Jae Sik YuSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. jsyu@bu.edu.
René BenndorfLeibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute, Beutenbergstraße 11a, 07745 Jena, Germany. rene.benndorf@hki-jena.de.
Sullim LeeCollege of Bio-Nano Technology, Gachon University, Seongnam 13120, Korea. sullimlee@gachon.ac.kr.
Dong-Soo LeeCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea. vet4animal@hotmail.com.
Jungmoo HuhCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Gwanak-gu, Seoul 08826, Korea. goodhjm112@snu.ac.kr.
Z Wilhelm de BeerForestry and Agriculture Biotechnology Institute, University of Pretoria, Pretoria 0028, South Africa. wilhelm.debeer@fabi.up.ac.za.ORCID 0000-0001-9758-8987
Yong Ho KimSKKU-Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Korea. yhkim94@skku.edu.
Christine BeemelmannsLeibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute, Beutenbergstraße 11a, 07745 Jena, Germany. Christine.beemelmanns@hki-jena.de.ORCID 0000-0002-9747-3423
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea. kkang@gachon.ac.kr.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. khkim83@skku.edu.ORCID 0000-0002-5285-9138
Gachon University · KRSungkyunkwan University · KRLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DESeoul National University · KRUniversity of Pretoria · ZA

Funding

Deutsche Stiftung für Herzforschung CRC1127 ChemBioSys and BE 4799/3-1Ministry of Trade, Industry & Energy (MOTIE, Korea) 20000105, Development of Cosmeceutical Material Platform using Organo-Nano Complexes based on Natural Active CompoundsNational Research Foundation of Korea 2018R1A2B2006879
6 · The paper itself

Abstract

In recent years, investigations into the biochemistry of insect-associated bacteria have increased. When combined with analytical dereplication processes, these studies provide a powerful strategy to identify structurally and/or biologically novel compounds. Non-ribosomally synthesized cyclic peptides have a broad bioactivity spectrum with high medicinal potential. Here, we report the discovery of three new cyclic tripeptides: natalenamides A⁻C (compounds

Indexed as

1-Methyl-3-isobutylxanthineActinomycetalesAnimalsAnti-Inflammatory AgentsAntineoplastic AgentsCell ProliferationIsopteraMacrophagesMelaninsMolecular StructureNeoplasmsPeptides, CyclicTumor Cells, Cultured1-Methyl-3-isobutylxanthineAnti-Inflammatory AgentsAntineoplastic AgentsMelaninsPeptides, CyclicActinomadura sp.fungus-growing termitenatalenamides A–Cskin-whitening effectstripeptides

Identifiers

PMID30453579
PMCPMC6278286
OpenAlexW2901618735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.