Evidence map›Paper›PMID 30453565›Full record

ReviewAntioxidants (Basel, Switzerland)2018

Structural/Functional Matches and Divergences of Phytoprostanes and Phytofurans with Bioactive Human Oxylipins.

Sonia Medina, Ángel Gil-Izquierdo, Thierry Durand, Federico Ferreres, Raúl Domínguez-Perles

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Epoxyalcohol Synthase Branch of Lipoxygenase Cascade.Current issues in molecular biology · 2024
    Review
  2. Wheat Oxylipins in Response to Aphids, COMolecules (Basel, Switzerland) · 2023
    Article
  3. Article
  4. A Phytoprostane fromInternational journal of molecular sciences · 2023
    Article
  5. Acute and Rapid Response ofPlants (Basel, Switzerland) · 2022
    Article
  6. Therapeutic Potential of Plant Oxylipins.International journal of molecular sciences · 2022
    Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonia MedinaCQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal. sonia.escudero@staff.uma.pt.
Ángel Gil-IzquierdoResearch Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), Campus University Espinardo, 30100 Murcia, Spain. angelgil@cebas.csic.es.ORCID 0000-0001-7646-0386
Thierry DurandInstitut des Biomolécules Max Mousseron (IBMM), UMR 5247-CNRS, Faculty of Pharmacy, University of Montpellier-ENSCM, 34093 Montpellier, France. Thierry.Durand@umontpellier.fr.
Federico FerreresResearch Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), Campus University Espinardo, 30100 Murcia, Spain. federico@cebas.csic.es.
Raúl Domínguez-PerlesResearch Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), Campus University Espinardo, 30100 Murcia, Spain. rdperles@cebas.csic.es.ORCID 0000-0001-6232-712X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structure-activity relationship (SAR) constitutes a crucial topic to discover new bioactive molecules. This approach initiates with the comparison of a target candidate with a molecule or a collection of molecules and their attributed biological functions to shed some light in the details of one or more SARs and subsequently using that information to outline valuable application of the newly identified compounds. Thus, while the empiric knowledge of medicinal chemistry is critical to these tasks, the results retrieved upon dedicated experimental demonstration retrieved resorting to modern high throughput analytical approaches and techniques allow to overwhelm the constraints adduced so far to the successful accomplishment of such tasks. Therefore, the present work reviews critically the evidences reported to date on the occurrence of phytoprostanes and phytofurans in plant foods, and the information available on their bioavailability and biological activity, shedding some light on the expectation waken up due to their structural similarities with prostanoids and isoprostanes.

Indexed as

biological activitymammals oxylipinsplant oxylipinsSARstructural analogy

Identifiers

PMID30453565
PMCPMC6262570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.