Evidence map›Paper›PMID 30453558›Full record

ArticleInternational journal of molecular sciences2018

Comparative Analyses of Cytochrome P450s and Those Associated with Secondary Metabolism in

Bongumusa Comfort Mthethwa, Wanping Chen, Mathula Lancelot Ngwenya, Abidemi Paul Kappo, Puleng Rosinah Syed, Rajshekhar Karpoormath, Jae-Hyuk Yu, David R Nelson, Khajamohiddin Syed

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Current issues in molecular biology · 2023
    Article
  5. Article
  6. Cytochromes P450 involved in bacterial RiPP biosyntheses.Journal of industrial microbiology & biotechnology · 2023
    Review
  7. Article
  8. Article
  9. Ancient Bacterial ClassInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. More P450s Are Involved in Secondary Metabolite Biosynthesis inInternational journal of molecular sciences · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Bongumusa Comfort MthethwaDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa. 07bcomfort@gmail.com.
Wanping ChenCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. chenwanping@mail.hzau.edu.cn.ORCID 0000-0002-6849-1972
Mathula Lancelot NgwenyaDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa. NgwenyaM@unizulu.ac.za.
Abidemi Paul KappoDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa. KappoA@unizulu.ac.za.ORCID 0000-0003-2521-8957
Puleng Rosinah SyedDepartment of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa. prosinah@gmail.com.
Rajshekhar KarpoormathDepartment of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa. Karpoormath@ukzn.ac.za.
Jae-Hyuk YuDepartment of Bacteriology, University of Wisconsin-Madison, 3155 MSB, 1550 Linden Drive, Madison, WI 53706, USA. jyu1@wisc.edu.ORCID 0000-0002-6530-8407
David R NelsonDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. drnelson1@gmail.com.ORCID 0000-0003-0583-5421
Khajamohiddin SyedDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa. khajamohiddinsyed@gmail.com.ORCID 0000-0002-1497-3570
University of Zululand · ZAUniversity of KwaZulu-Natal · ZAHuazhong Agricultural University · CNUniversity of Tennessee Health Science Center · USUniversity of Wisconsin–Madison · US

Funding

National Research Foundation 114159University of Zululand C686
6 · The paper itself

Abstract

Cytochrome P450 monooxygenases (CYPs/P450s) are among the most catalytically-diverse enzymes, capable of performing enzymatic reactions with chemo-, regio-, and stereo-selectivity. Our understanding of P450s' role in secondary metabolite biosynthesis is becoming broader. Among bacteria,

Indexed as

Secondary MetabolismBacillusCytochrome P-450 Enzyme SystemMultigene FamilyPhylogenySpecies SpecificityCytochrome P-450 Enzyme SystemAntibioticsBacillusbiosynthetic gene clusterscomparative analysiscytochrome P450 monooxygenaseMycobacteriumP450 diversity percentageP450 profilingsecondary metabolites

Identifiers

PMID30453558
PMCPMC6275058
OpenAlexW2900974595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.