Evidence map›Paper›PMID 30453553›Full record

Trial reportInternational journal of environmental research and public health2018

Breaking up Sedentary Time in Overweight/Obese Adults on Work Days and Non-Work Days: Results from a Feasibility Study.

Nathan P De Jong, Isaac Debache, Zhaoxing Pan, Mael Garnotel, Kate Lyden, Cédric Sueur, Chantal Simon, Daniel H Bessesen, Audrey Bergouignan

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. The role of physical activity in the regulation of body weight: The overlooked contribution of light physical activity and sedentary behaviors.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Nathan P De JongDivision of Endocrinology, Metabolism, and Diabetes and Anschutz Health and Wellness Center, University of Colorado, School of Medicine, Aurora, CO 80045, USA. nathan.dejong@ucdenver.edu.ORCID 0000-0003-0298-6777
Isaac DebacheInstitut Pluridisciplinaire Hubert Curien, Université de Strasbourg, CNRS 67000 Strasbourg, France. isaac.debache@iphc.cnrs.fr.
Zhaoxing PanDepartment of Biostatistics and Informatics, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA. zhaoxing.pan@ucdenver.edu.
Mael GarnotelCARMEN, CRNH, INSERM U1060/University of Lyon 1/INRA U1235 Lyon, France. ext-mael.garnotel@chu-lyon.fr.
Kate LydenKAL Research and Consulting LLC, Denver, CO 80002, USA. katelyden6@gmail.com.
Cédric SueurInstitut Pluridisciplinaire Hubert Curien, Université de Strasbourg, CNRS 67000 Strasbourg, France. Cedric.sueur@iphc.cnrs.fr.
Chantal SimonLaboratoire de Biochimie CHLS 69310 Pierre Bénite, France. chantal@simon-bertrand.com.ORCID 0000-0002-7820-3233
Daniel H BessesenDivision of Endocrinology, Metabolism, and Diabetes and Anschutz Health and Wellness Center, University of Colorado, School of Medicine, Aurora, CO 80045, USA. daniel.bessesen@ucdenver.edu.
Audrey BergouignanDivision of Endocrinology, Metabolism, and Diabetes and Anschutz Health and Wellness Center, University of Colorado, School of Medicine, Aurora, CO 80045, USA. Audrey.bergouignan@iphc.cnrs.fr.ORCID 0000-0002-1266-5144
Centre National de la Recherche Scientifique · FRUniversity of Colorado Anschutz Medical Campus · USDenver Health Medical Center · USUniversité Claude Bernard Lyon 1 · FR

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)T42OH009229 · OH · UNIVERSITY OF COLORADO DENVER · PI NEWMAN, LEE S · 2007 to 2024
$28.8M
Breaking-up sitting to offset sedentary behaviors-induced metabolic alterationsK99DK100465 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BERGOUIGNAN, AUDREY · 2014 to 2015
$179k
CDC NIOSH Mountain and Plains Education and Research Center T42OH009229-10NCATS NIH HHS UL1 TR002535NIH HHS 5P30DK048520NIH HHS K99DK100465NIH HHS UL1 TR001082NIOSH CDC HHS T42 OH009229
6 · The paper itself

Abstract

Office workers are vulnerable to the adverse health effects of sedentary behavior (i.e., sitting time). Increasing physical activity and preventing time spent sitting is an occupational health priority. This randomized crossover design study compared the short-term (3-days) effects of hourly interruptions of sedentary time with 5-min micrrobouts of activity for 9 hours (MICRO) to a sedentary control condition (SED) and a duration-matched continuous single bout of physical activity (45-min/d, ONE) condition on inclinometer-derived sitting-time on work and non-work days in sedentary overweight/obese adults. Differences in sitting/lying, standing, stepping, number of sit/stand transitions, time spent in moderate and vigorous activity (MVPA), energy expenditure, self-perceived vigor and fatigue, and insulin sensitivity were also examined. Twenty-two participants (10M/12F; 31.7 ± 1.3 year old BMI 30.4 ± 0.5 kg/m²) completed all conditions. No between-condition effects were observed in sitting-time and sit/stand transitions. Both interventions increased daily steps, MVPA and energy expenditure with increases being greater in ONE than MICRO. Feelings of vigor and fasting insulin sensitivity were also improved. Participants reported less fatigue with MICRO than SED and ONE. Both interventions increase physical activity and energy expenditure in occupational and leisure-time contexts. The sustainability of these effects over the long term and on health outcomes will need to be tested in future studies.

Indexed as

ExerciseOccupational HealthSedentary BehaviorAdultCross-Over StudiesEnergy MetabolismFatigueFeasibility StudiesFemaleHumansLeisure ActivitiesMaleObesityOverweightPostureTime Factorsactivity energy expenditurefatigueinsulin sensitivitymicroboutsMVPAphysical activitysedentary behaviorssittingvigor

Identifiers

PMID30453553
PMCPMC6266976
OpenAlexW2901090929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.