Evidence map›Paper›PMID 30453505›Full record

ArticleNutrients2018

Regular Practice of Moderate Physical Activity by Older Adults Ameliorates Their Anti-Inflammatory Status.

Miguel D Ferrer, Xavier Capó, Miquel Martorell, Carla Busquets-Cortés, Cristina Bouzas, Sandra Carreres, David Mateos, Antoni Sureda, Josep A Tur, Antoni Pons

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Miguel D FerrerGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. miguel-david.ferrer@uib.es.ORCID 0000-0003-1924-7727
Xavier CapóGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. xavier.capo@uib.es.
Miquel MartorellGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. martorellpons@gmail.com.ORCID 0000-0003-3183-7623
Carla Busquets-CortésGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. carla_busquets@hotmail.com.
Cristina BouzasGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. cristina.bouzas@uib.es.
Sandra CarreresGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. sandra.carreres@uib.cat.
David MateosGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. david-mateos@hotmail.com.
Antoni SuredaGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. antoni.sureda@uib.es.ORCID 0000-0001-8656-6838
Josep A TurGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. pep.tur@uib.es.ORCID 0000-0002-6940-0761
Antoni PonsGrup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain. antonipons@uib.es.ORCID 0000-0003-2447-3868
Instituto de Salud Carlos III · ESUniversity of Concepción · CL

Funding

Govern de les Illes Balears 35/2011Govern de les Illes Balears AAEE26/2017Instituto de Salud Carlos III 11/01791Instituto de Salud Carlos III 14/00636Instituto de Salud Carlos III CB12/03/30038Instituto de Salud Carlos III RD06/0045/1004
6 · The paper itself

Abstract

A chronic inflammatory state is a major characteristic of the aging process, and physical activity is proposed as a key component for healthy aging. Our aim was to evaluate the body composition, hypertension, lipid profile, and inflammatory status of older adults, and these factors' association with physical activity. A total of 116 elderly volunteers were categorized into terciles of quantitative metabolic equivalents of task (MET). Subjects in the first and third terciles were defined as sedentary and active subjects, respectively. Anthropometric and biochemical parameters, hemograms, and inflammatory markers were measured in plasma or peripheral mononuclear blood cells (PBMCs). The active groups exercised more than their sedentary counterparts. The practice of physical activity was accompanied by lower weight, fat mass, body mass index, and diastolic blood pressure when compared to a more sedentary life-style. Physical activity also lowered the haematocrit and total leukocyte, neutrophil, and lymphocyte counts. The practice of exercise induced a decrease in the IL-6 circulating levels and the TLR2 protein levels in PBMCs, while the expression of the anti-inflammatory IL-10 was activated in active subjects. The regular practice of physical activity exerts beneficial effects on body composition and the anti-inflammatory status of old people.

Indexed as

ExerciseAgedAged, 80 and overAnthropometryAntigens, CDBiomarkersBlood GlucoseBody CompositionCell Adhesion MoleculesCholesterolCreatinineCross-Sectional StudiesCytokinesFemaleHemoglobinsHumansAntigens, CDBiomarkersBlood GlucoseCell Adhesion MoleculesCholesterolCreatinineCytokinesHemoglobinsICAM3 protein, humanIL6 protein, humanInterleukin-6L-SelectinTriglyceridesTumor Necrosis Factor-alphaUric Acidimmunityinflammationmetabolismphysical activity

Identifiers

PMID30453505
PMCPMC6266855
OpenAlexW2901325888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.