Evidence map›Paper›PMID 30453481›Full record

ArticleMolecules (Basel, Switzerland)2018

Development of New Analytical Microwave-Assisted Extraction Methods for Bioactive Compounds from Myrtle (

Ana V González de Peredo, Mercedes Vázquez-Espinosa, Estrella Espada-Bellido, Ana Jiménez-Cantizano, Marta Ferreiro-González, Antonio Amores-Arrocha, Miguel Palma, Carmelo G Barroso, Gerardo F Barbero

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Phytochemical Profiling of Processed Açaí Pulp (Antioxidants (Basel, Switzerland) · 2025
    Article
  2. WildFoods (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Extraction of Antioxidant Compounds from Onion Bulb (Antioxidants (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana V González de PeredoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. ana.velascogope@uca.es.ORCID 0000-0002-0161-3533
Mercedes Vázquez-EspinosaDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. mercedes.vazquez@uca.es.ORCID 0000-0002-7254-9153
Estrella Espada-BellidoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. estrella.espada@uca.es.ORCID 0000-0002-8166-2510
Ana Jiménez-CantizanoDepartment of Chemical Engineering and Food Technology, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. ana.jimenezcantizano@uca.es.
Marta Ferreiro-GonzálezDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. marta.ferreiro@uca.es.ORCID 0000-0003-0870-403X
Antonio Amores-ArrochaDepartment of Chemical Engineering and Food Technology, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. antonio.amores@uca.es.ORCID 0000-0001-9690-591X
Miguel PalmaDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. miguel.palma@uca.es.
Carmelo G BarrosoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. carmelo.garcia@uca.es.
Gerardo F BarberoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Agrifood Campus of International Excellence (ceiA3), IVAGRO, Puerto Real, 11510 Cadiz, Spain. gerardo.fernandez@uca.es.ORCID 0000-0001-7302-6605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenolic compounds and anthocyanins present in myrtle berries are responsible for its beneficial health properties. In the present study, a new, microwave-assisted extraction for the analysis of both phenolic compounds and anthocyanins from myrtle pulp has been developed. Different extraction variables, including methanol composition, pH, temperature, and sample⁻solvent ratio were optimized by applying a Box⁻Behnken design and response surface methodology. Methanol composition and pH were the most influential variables for the total phenolic compounds (58.20% of the solvent in water at pH 2), and methanol composition and temperature for anthocyanins (50.4% of solvent at 50 °C). The methods developed showed high repeatability and intermediate precision (RSD < 5%). Both methods were applied to myrtle berries collected in two different areas of the province of Cadiz (Spain). Hierarchical clustering analysis results show that the concentration of bioactive compounds in myrtle is related to their geographical origin.

Indexed as

MicrowavesAnthocyaninsLiquid-Liquid ExtractionMethanolMyrtusPhenolsPlant ExtractsAnthocyaninsMethanolPhenolsPlant Extractsanthocyaninsbioactive compoundsBox–Behnken designmicrowave-assisted extractionmyrtleMyrtus communisphenolic compounds

Identifiers

PMID30453481
PMCPMC6278529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.