Evidence map›Paper›PMID 30452541›Full record

ArticleAmerican journal of epidemiology2019

Associations Between Features of Placental Morphology and Birth Weight in Dichorionic Twins.

Alexa A Freedman, Carol J Hogue, Carmen J Marsit, Augustine Rajakumar, Alicia K Smith, Katherine L Grantz, Robert L Goldenberg, Donald J Dudley, George R Saade, Robert M Silver and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Alexa A FreedmanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Carol J HogueDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Carmen J MarsitDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Augustine RajakumarDepartment of Gynecology and Obstetrics, School of Medicine, Emory University, Atlanta, Georgia.
Alicia K SmithDepartment of Gynecology and Obstetrics, School of Medicine, Emory University, Atlanta, Georgia.
Katherine L GrantzDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York.
Donald J DudleyDepartment of Obstetrics and Gynecology, School of Medicine, University of Virginia, Charlottesville, Virginia.
George R SaadeDepartment of Obstetrics and Gynecology, University of Texas Medical Branch at Galveston, University of Texas, Galveston, Texas.
Robert M SilverDepartment of Obstetrics and Gynecology, School of Medicine, University of Utah, Salt Lake City, Utah.
Karen J GibbinsDepartment of Obstetrics and Gynecology, School of Medicine, University of Utah, Salt Lake City, Utah.
Radek BukowskiDepartment of Women's Health, Dell Medical School, University of Texas at Austin, Austin, Texas.
Carolyn Drews-BotschDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Emory University · USUniversity of Utah · USColumbia University Irving Medical Center · USNational Institutes of Health · USThe University of Texas at Austin · USThe University of Texas Medical Branch at Galveston · USUniversity of Virginia · US

Funding

Stillbirth NetworkU01HD045954 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2003 to 2009
$8.4M
Research on the Scope and Causes of Stillbirth in the USU10HD045944 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2003 to 2009
$2.7M
San Antonio Center for the Study of StillbirthU10HD045955 · NICHD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DUDLEY, DONALD J · 2003 to 2009
$2.4M
Research on the Scope and Causes of Stillbirth in the USU10HD045925 · NICHD · EMORY UNIVERSITY · PI HOGUE, CAROL · 2003 to 2009
$2.3M
RESEARCH ON SCOPE &CAUSES OF STILLBIRTH IN THE USU10HD045953 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI COUSTAN, DONALD R · 2003 to 2009
$2.3M
Training in Reproductive, Perinatal, Pediatric EpidemiologyT32HD052460 · NICHD · EMORY UNIVERSITY · PI DREWS-BOTSCH, CAROLYN DAWSON · 2006 to 2015
$2.2M
Scope and Causes of StillbirthU10HD045952 · NICHD · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SAADE, GEORGE R. · 2003 to 2009
$1.9M
Features of placental morphology, fetal growth, and adverse cognitive outcomes in childhoodF31HD092025 · NICHD · EMORY UNIVERSITY · PI FREEDMAN, ALEXA · 2017 to 2017
$37k
NICHD NIH HHS F31 HD092025NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002INICHD NIH HHS HHSN275200800003CNICHD NIH HHS HHSN275200800003INICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275200800014CNICHD NIH HHS HHSN275200800028CNICHD NIH HHS HHSN275201000009CNICHD NIH HHS HHSN275201400001CNICHD NIH HHS T32 HD052460NICHD NIH HHS U01 HD045954NICHD NIH HHS U10 HD045925NICHD NIH HHS U10 HD045944NICHD NIH HHS U10 HD045952NICHD NIH HHS U10 HD045953NICHD NIH HHS U10 HD045955
6 · The paper itself

Abstract

Low birth weight is associated with perinatal and long-term morbidity and mortality, and may be a result of abnormal placental development and function. In studies of singletons, associations have been reported between features of placental morphology and birth weight. Evaluating similar associations within twin pairs offers a unique opportunity to control for key confounders shared within a twin pair, including gestational age, parental characteristics, and intrauterine environment. Data from 3 studies in the United States that were completed from 2012 to 2013, 2006 to 2008, and 1959 to 1966 were used in our analysis of 208 sets of dichorionic twins with unfused placentas. We used linear regression to model difference in birth weight within a twin pair as a function of differences in placental characteristics (i.e., thickness, 2-dimensional surface area, intraplacental difference in diameter). After controlling for sex discordance, a 75.3- cm2 difference in placental surface area, which reflects the interquartile range, was associated with a difference in birth weight of 142.1 g (95% confidence interval (CI): 62.9, 221.3). The magnitude of the association also may be larger for same-sex male pairs than same-sex female pairs (males: 265.8 g, 95% CI: 60.8, 470.8; females: 133.0 g, 95% CI: 15.7, 250.3). Strong associations between surface area and birth weight are consistent with reported results for singleton pregnancies.

Indexed as

Birth WeightAdultFemaleGestational AgeHumansInfant, NewbornMalePlacentaPregnancyTwinning, DizygoticTwins, Dizygoticbirth weightplacentatwins

Identifiers

PMID30452541
PMCPMC6395169
OpenAlexW2911927259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.