Evidence map›Paper›PMID 30452432›Full record

ArticleJournal of X-ray science and technology2019

Expert knowledge-infused deep learning for automatic lung nodule detection.

Jiaxing Tan, Yumei Huo, Zhengrong Liang, Lihong Li

Abstract read
In one paragraph

Article in Journal of X-ray science and technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
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  10. Developing global image feature analysis models to predict cancer risk and prognosis.Visual computing for industry, biomedicine, and art · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiaxing TanDepartment of Computer Science, City University of New York, the Graduate Center, NY, USA.
Yumei HuoDepartment of Computer Science, City University of New York at CSI, NY, USA.
Zhengrong LiangDepartment of Radiology, State University of New York at Stony Brook, NY, USA.
Lihong LiDepartment of Engineering Science and Physics, City University of New York at CSI, NY, USA.

Funding

Advancing Virtual Colonoscopy for Early Cancer ScreeningR01CA206171 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI LIANG, JEROME Z · 2016 to 2020
$2.0M
NCI NIH HHS R01 CA206171
6 · The paper itself

Abstract

backgroundComputer aided detection (CADe) of pulmonary nodules from computed tomography (CT) is crucial for early diagnosis of lung cancer. Self-learned features obtained by training datasets via deep learning have facilitated CADe of the nodules. However, the complexity of CT lung images renders a challenge of extracting effective features by self-learning only. This condition is exacerbated for limited size of datasets. On the other hand, the engineered features have been widely studied.

objectiveWe proposed a novel nodule CADe which aims to relieve the challenge by the use of available engineered features to prevent convolution neural networks (CNN) from overfitting under dataset limitation and reduce the running-time complexity of self-learning.

methodsThe CADe methodology infuses adequately the engineered features, particularly texture features, into the deep learning process.

resultsThe methodology was validated on 208 patients with at least one juxta-pleural nodule from the public LIDC-IDRI database. Results demonstrated that the methodology achieves a sensitivity of 88% with 1.9 false positives per scan and a sensitivity of 94.01% with 4.01 false positives per scan.

conclusionsThe methodology shows high performance compared with the state-of-the-art results, in terms of accuracy and efficiency, from both existing CNN-based approaches and engineered feature-based classifications.

Indexed as

Deep LearningHumansKnowledge BasesLung NeoplasmsMultiple Pulmonary NodulesNeural Networks, ComputerRadiographic Image Interpretation, Computer-AssistedSensitivity and SpecificitySolitary Pulmonary NoduleTomography, X-Ray Computedcomputed tomography (CT) imagingComputer aided detection (CADe)deep learningimage features analysispulmonary nodules

Identifiers

PMID30452432
PMCPMC6453714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.