Evidence map›Paper›PMID 30452022›Full record

ArticleChemical communications (Cambridge, England)2018

Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs.

Nils Hellwig, Oliver Peetz, Zainab Ahdash, Igor Tascón, Paula J Booth, Vedrana Mikusevic, Marina Diskowski, Argyris Politis, Yvonne Hellmich, Inga Hänelt and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 54 citations in OpenAlex.

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  20. Nanodiscs and Mass Spectrometry: Making Membranes Fly.International journal of mass spectrometry · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nils HellwigInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 7, 60438 Frankfurt, Germany. morgner@chemie.uni-frankfurt.de.
Oliver Peetz
Zainab Ahdash
Igor Tascón
Paula J Booth
Vedrana Mikusevic
Marina Diskowski
Argyris Politis
Yvonne Hellmich
Inga Hänelt
Eamonn Reading
Nina Morgner
Goethe University Frankfurt · DEKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Other than more widely used methods, the use of styrene maleic acid allows the direct extraction of membrane proteins from the lipid bilayer into SMALPs keeping it in its native lipid surrounding. Here we present the combined use of SMALPs and LILBID-MS, allowing determination of oligomeric states of membrane proteins of different functionality directly from the native nanodiscs.

Indexed as

Lipid BilayersLipidsMaleatesMass SpectrometryMembrane ProteinsModels, MolecularParticle SizeStyreneLipid BilayersLipidsMaleatesmaleic acidMembrane ProteinsStyrene

Identifiers

PMID30452022
PMCPMC6289172
OpenAlexW2901913378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.