Evidence map›Paper›PMID 30451886›Full record

ArticleScientific reports2018

Atypical postural control can be detected via computer vision analysis in toddlers with autism spectrum disorder.

Geraldine Dawson, Kathleen Campbell, Jordan Hashemi, Steven J Lippmann, Valerie Smith, Kimberly Carpenter, Helen Egger, Steven Espinosa, Saritha Vermeer, Jeffrey Baker and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Digital tools for direct assessment of autism risk during early childhood: A systematic review.Autism : the international journal of research and practice · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology.Autism research : official journal of the International Society for Autism Research · 2026
    Article
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  9. Autism Digital Phenotyping in Preschool- and School-Age Children.Autism research : official journal of the International Society for Autism Research · 2025
    Article
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  15. Review
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  17. Relationship between quantitative digital behavioral features and clinical profiles in young autistic children.Autism research : official journal of the International Society for Autism Research · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Geraldine DawsonDuke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA. geraldine.dawson@duke.edu.ORCID http://orcid.org/0000-0003-1410-2764
Kathleen CampbellUniversity of Utah, Salt Lake City, Utah, USA.
Jordan HashemiDuke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Steven J LippmannDepartment of Population Health Sciences, Duke University, Durham, North Carolina, USA.ORCID http://orcid.org/0000-0003-2838-1186
Valerie SmithDepartment of Population Health Sciences, Duke University, Durham, North Carolina, USA.
Kimberly CarpenterDuke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Helen EggerNYU Langone Child Study Center, New York University, New York, New York, USA.
Steven EspinosaDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina, USA.
Saritha VermeerDuke Center for Autism and Brain Development, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Jeffrey BakerDepartment of Pediatrics, Duke University, Durham, NC, USA.
Guillermo SapiroDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina, USA.
Duke University · USNew York University · USUniversity of Utah · US

Funding

Recruitment and Assessment CoreP50HD093074 · NICHD · DUKE UNIVERSITY · PI SCOTT N COMPTON · 2017 to 2026
$27.6M
Scalable Computational Platform For Active Closed-Loop Behavioral Coding in Autism Spectrum DisorderR01MH120093 · NIMH · DUKE UNIVERSITY · PI DAWSON, GERALDINE, SAPIRO, GUILLERMO R · 2019 to 2022
$1.6M
Duke CTSA (Composite)TL1TR001116 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, KRAFT, MONICA · 2013 to 2017
$1.2M
NICHD NIH HHS P50 HD093074NIMH NIH HHS R01 MH120093
6 · The paper itself

Abstract

Evidence suggests that differences in motor function are an early feature of autism spectrum disorder (ASD). One aspect of motor ability that develops during childhood is postural control, reflected in the ability to maintain a steady head and body position without excessive sway. Observational studies have documented differences in postural control in older children with ASD. The present study used computer vision analysis to assess midline head postural control, as reflected in the rate of spontaneous head movements during states of active attention, in 104 toddlers between 16-31 months of age (Mean = 22 months), 22 of whom were diagnosed with ASD. Time-series data revealed robust group differences in the rate of head movements while the toddlers watched movies depicting social and nonsocial stimuli. Toddlers with ASD exhibited a significantly higher rate of head movement as compared to non-ASD toddlers, suggesting difficulties in maintaining midline position of the head while engaging attentional systems. The use of digital phenotyping approaches, such as computer vision analysis, to quantify variation in early motor behaviors will allow for more precise, objective, and quantitative characterization of early motor signatures and potentially provide new automated methods for early autism risk identification.

Indexed as

AlgorithmsHead MovementsPostureAttentionAutism Spectrum DisorderCase-Control StudiesChild, PreschoolDiagnosis, Computer-AssistedFemaleHumansImage Processing, Computer-AssistedInfantMaleMicroscopy, Video

Identifiers

PMID30451886
PMCPMC6242931
OpenAlexW2900541008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.