ReviewHuman brain mapping2019
Prenatal exposures and infant brain: Review of magnetic resonance imaging studies and a population description analysis.
Review in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 57 citations in OpenAlex.
- Investigating the influence of maternal prenatal BMI and perinatal depressive symptoms on neonatal brain network dynamics.Pediatric research · 2026Article
- Adaptive Skills May Moderate the Association between Prenatal Stress Exposure and Limbic Brain Activation: A Developmental Functional Magnetic Resonance Imaging Study of Superstorm Sandy Exposure.Developmental neuroscience · 2026Article
- Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- COVID-19 Pandemic-Related Prenatal Distress and Infant Functional Brain Development.JAACAP open · 2025Article
- Unveiling GABA and Serotonin Interactions During Neurodevelopment to Re-Open Adult Critical Periods for Neuropsychiatric Disorders.International journal of molecular sciences · 2025Review
- Article
- Prenatal substance exposure and infant neurodevelopment: a review of magnetic resonance imaging studies.Frontiers in human neuroscience · 2025Review
- Assessing prenatal and early childhood social and environmental determinants of health in the HEALthy Brain and Child Development Study (HBCD).Developmental cognitive neuroscience · 2024Article
- Maternal anxiety during pregnancy is associated with weaker prefrontal functional connectivity in adult offspring.Brain imaging and behavior · 2023Article
- Maternal psychological distress associates with alterations in resting-state low-frequency fluctuations and distal functional connectivity of the neonate medial prefrontal cortex.The European journal of neuroscience · 2023Article
- Prenatal and early-life environmental factors, family demographics and cortical brain anatomy in 5-year-olds: an MRI study from FinnBrain Birth Cohort.Brain imaging and behavior · 2022Article
- Subcortical and hippocampal brain segmentation in 5-year-old children: Validation of FSL-FIRST and FreeSurfer against manual segmentation.The European journal of neuroscience · 2022Article
- Mendelian randomization study on the causal effects of COVID-19 on childhood intelligence.Journal of medical virology · 2022Article
- Deleterious effects of nervous system in the offspring following maternal SARS-CoV-2 infection during the COVID-19 pandemic.Translational psychiatry · 2022Review
- Association of Prenatal Exposure to Early-Life Adversity With Neonatal Brain Volumes at Birth.JAMA network open · 2022Article
- Brain organoid-on-chip system to study the effects of breast cancer derived exosomes on the neurodevelopment of brain.Cell regeneration (London, England) · 2022Article
- Auditory Mismatch Responses to Emotional Stimuli in 3-Year-Olds in Relation to Prenatal Maternal Depression Symptoms.Frontiers in neuroscience · 2022Article
- Feasibility of FreeSurfer Processing for T1-Weighted Brain Images of 5-Year-Olds: Semiautomated Protocol of FinnBrain Neuroimaging Lab.Frontiers in neuroscience · 2022Article
- Maternal pre-pregnancy BMI associates with neonate local and distal functional connectivity of the left superior frontal gyrus.Scientific reports · 2021Observational
- Central white matter integrity alterations in 2-3-year-old children following prenatal alcohol exposure.Drug and alcohol dependence · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 3 countries.
Funding
Abstract
Brain development is most rapid during the fetal period and the first years of life. This process can be affected by many in utero factors, such as chemical exposures and maternal health characteristics. The goal of this review is twofold: to review the most recent findings on the effects of these prenatal factors on the developing brain and to qualitatively assess how those factors were generally reported in studies on infants up to 2 years of age. To capture the latest findings in the field, we searched articles from PubMed 2012 onward with search terms referring to magnetic resonance imaging (MRI), brain development, and infancy. We identified 19 MRI studies focusing on the effects of prenatal environment and summarized them to highlight the recent advances in the field. We assessed population descriptions in a representative sample of 67 studies and conclude that prenatal factors that have been shown to affect brain metrics are not generally reported comprehensively. Based on our findings, we propose some improvements for population descriptions to account for plausible confounders and in time enable reliable meta-analyses to be performed. This could help the pediatric neuroimaging field move toward more reliable identification of biomarkers for developmental outcomes and to better decipher the nuances of normal and abnormal brain development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.