Evidence map›Paper›PMID 30450768›Full record

ReviewJournal of cellular and molecular medicine2019

Immunometabolism features of metabolic deregulation and cancer.

Xue Wang, Feng-Feng Ping, Sahar Bakht, Jingjing Ling, Waseem Hassan

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells.Journal of visualized experiments : JoVE · 2025
    Article
  3. Car T Cells in Solid Tumors: Overcoming Obstacles.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Lipid-loaded macrophages as new therapeutic target in cancer.Journal for immunotherapy of cancer · 2022
    Review
  6. Observational
  7. Advancing to the era of cancer immunotherapy.Cancer communications (London, England) · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Ovariectomy Activates Chronic Low-Grade Inflammation Mediated by Memory T Cells, Which Promotes Osteoporosis in Mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  12. Review
  13. Immunometabolism features of metabolic deregulation and cancer.Journal of cellular and molecular medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xue WangWuxi School of Medicine, Jiangnan University, Wuxi, China.ORCID 0000-0002-2825-3988
Feng-Feng PingWuxi People's Hospital, Nanjing Medical University, Wuxi, China.
Sahar BakhtFaculty of Pharmacy and alternative medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Jingjing LingWuxi Children's Hospital, Wuxi, China.
Waseem HassanDepartment of Pharmacy, COMSATS University Islamabad, Lahore, Pakistan.ORCID 0000-0002-0197-1736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunometabolism is a branch dealing at the interface of immune functionalities and metabolic regulations. Considered as a bidirectional trafficking, metabolic contents and their precursors bring a considerable change in immune cells signal transductions which as a result affect the metabolic organs and states as an implication. Lipid metabolic ingredients form a major chunk of daily diet and have a proven contribution in immune cells induction, which then undergo metabolic pathway shuffling inside their ownself. Lipid metabolic states activate relevant metabolic pathways inside immune cells that in turn prime appropriate responses to outside environment in various states including lipid metabolic disorders itself and cancers as an extension. Although data on Immunometabolism are still growing, but scientific community need to adjust and readjust according to recent data on given subject. This review attempts to provide current important data on Immunometabolism and consequently its metabolic ramifications. Incumbent data on various lipid metabolic deregulations like obesity, metabolic syndrome, obese asthma and atherosclerosis are analysed. Further, metabolic repercussions on cancers and its immune modalities are also analysed.

Indexed as

AnimalsAsthmaAtherosclerosisDisease Models, AnimalGene Expression Regulation, NeoplasticHumansImmunity, InnateLipid MetabolismLymphocyte SubsetsMacrophagesMetabolic Networks and PathwaysMiceNeoplasm ProteinsNeoplasmsObesitySignal TransductionNeoplasm Proteinscancerimmunometabolismmetabolic deregulationstumour microenvironment

Identifiers

PMID30450768
PMCPMC6349168

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.