Evidence map›Paper›PMID 30450486›Full record

ArticleEpilepsia open2018

A companion to the preclinical common data elements and case report forms for rodent EEG studies. A report of the TASK3 EEG Working Group of the ILAE/AES Joint Translational Task Force.

Tomonori Ono, Joost Wagenaar, Filippo S Giorgi, Petr Fabera, Ryosuke Hanaya, John Jefferys, Jason T Moyer, Lauren C Harte-Hargrove, Aristea S Galanopoulou

Abstract read
In one paragraph

Article in Epilepsia open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomonori OnoDepartment of Neurosurgery Epilepsy Center National Nagasaki, Medical Center Omura Nagasaki Japan.
Joost WagenaarDepartment of Neurology Center for Neuroengineering and Therapeutics University of Pennsylvania Philadelphia Pennsylvania U.S.A.
Filippo S GiorgiNeurology Unit Epilepsy Center University Hospital University of Pisa Pisa Italy.
Petr FaberaDepartment of Developmental Epileptology Institute of Physiology Czech Academy of Sciences Department of Neurology Second Faculty of Medicine Charles University and Motol University Hospital Prague Czech Republic.
Ryosuke HanayaDepartment of Neurosurgery and Epilepsy Center Kagoshima University Hospital Kagoshima Japan.
John JefferysDepartment of Pharmacology University of Oxford Oxford United Kingdom.
Jason T MoyerDepartment of Neurology Center for Neuroengineering and Therapeutics University of Pennsylvania Philadelphia Pennsylvania U.S.A.
Lauren C Harte-HargroveJoint Translational Research Task Force of the ILAE AES/ILAE West Hartford Connecticut U.S.A.
Aristea S GalanopoulouLaboratory of Developmental Epilepsy Isabelle Rapin Division of Child Neurology Saul R. Korey Department of Neurology Dominick P. Purpura Department of Neuroscience Albert Einstein College of Medicine Montefiore/Einstein Epilepsy Center Bronx New York U.S.A.

Funding

The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) Public Engagement CoreU54NS100064 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOGA, ARTHUR W · 2017 to 2021
$21.7M
GABA-inflammation interplay in infantile spasmsR01NS091170 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GALANOPOULOU, ARISTEA S · 2015 to 2020
$1.9M
NINDS NIH HHS R01 NS091170NINDS NIH HHS U54 NS100064
6 · The paper itself

Abstract

Electroencephalography (EEG) is commonly used in epilepsy and neuroscience research to study brain activity. The principles of EEG recording such as signal acquisition, digitization, and conditioning share similarities between animal and clinical EEG systems. In contrast, preclinical EEG studies demonstrate more variability and diversity than clinical studies in the types and locations of EEG electrodes, methods of data analysis, and scoring of EEG patterns and associated behaviors. The TASK3 EEG working group of the International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force has developed a set of preclinical common data elements (CDEs) and case report forms (CRFs) for recording, analysis, and scoring of animal EEG studies. This companion document accompanies the first set of proposed preclinical EEG CRFs and is intended to clarify the CDEs included in these worksheets. We provide 7 CRF and accompanying CDE modules for use by the research community, covering video acquisition, electrode information, experimental scheduling, and scoring of EEG activity. For ease of use, all data elements and input ranges are defined in supporting Excel charts (Appendix S1).

Indexed as

Case report formCommon data elementsEEGEpilepsyGuidelinesPreclinical researchRodent model

Identifiers

PMID30450486
PMCPMC6210053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.