ArticleKidney international reports2018
Secondary Oxalate Nephropathy: A Systematic Review.
Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 105 citations in OpenAlex.
- The Kidneys Went Nuts: Oxalate Nephropathy From Excessive Cashew Nut Consumption.Kidney medicine · 2026Article
- Severe Acute Kidney Injury Following Whipple Procedure.Kidney360 · 2026Article
- Kidney transplantation in obese Black patients: Strategies to improve access and outcomes.World journal of nephrology · 2026Review
- Case Report: A case of acute kidney injury due to star fruit-infused liquor.Frontiers in medicine · 2026Article
- Acute kidney injury induced by topical hair straightening products: A systematic review.World journal of nephrology · 2025Article
- Acute oxalate nephropathy seven years post Roux-en-Y gastric bypass surgery without excessive vitamin C intake: a case report.BMC geriatrics · 2025Article
- Oxalate nephropathy causing renal failure in small bowel Crohn's disease: a case report.Journal of medical case reports · 2025Article
- Dietary Oxalate Nephropathy Due to Pureed Feeds.Kidney medicine · 2025Article
- Hyperoxaluria: Diagnosis and Treatment.The Urologic clinics of North America · 2025Review
- NLRP3 inflammasome activation and macrophage distribution in kidney tissues from patients with acute oxalate nephropathy.Kidney research and clinical practice · 2025Article
- A 64-Year-Old Woman with Diabetes Mellitus Associated with Increased Urinary Oxalate Excretion Presenting with Acute Kidney Injury Due to Acute Oxalate Nephropathy.The American journal of case reports · 2025Article
- Real-world outcomes of managing autosomal-dominant polycystic kidney disease using a medical food as part of a nutrition and lifestyle program to improve renal and metabolic health.Frontiers in nutrition · 2025Article
- Current global vitamin and cofactor prescribing practices for primary mitochondrial diseases: Results of a European reference network survey.Journal of inherited metabolic disease · 2025Article
- A case report of renal oxalosis and secondary hyperoxaluria due to chronic high vitamin C consumption.Clinical nephrology. Case studies · 2025Article
- Article
- Navigating the Evolving Landscape of Primary Hyperoxaluria: Traditional Management Defied by the Rise of Novel Molecular Drugs.Biomolecules · 2024Review
- Clinicopathologic Characteristics, Etiologies, and Outcome of Secondary Oxalate Nephropathy.Mayo Clinic proceedings · 2024Article
- Diet-induced hyperoxaluria: A case based mini-review.Clinical nephrology. Case studies · 2024Article
- Oxalate Nephropathy and the Mechanism of Oxalate-Induced Kidney Injury.Kidney diseases (Basel, Switzerland) · 2023Review
- Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLittle is known of the clinical outcomes of secondary oxalate nephropathy. To inform clinical practice, we performed a systematic review of case reports and case series to examine the clinical characteristics and outcomes of patients with secondary oxalate nephropathy.
methodsElectronic databases were searched for case reports and case series of individual cases or cohorts of patients with biopsy-proven oxalate nephropathy in native or transplanted kidneys from 1950 until January 2018.
resultsFifty-seven case reports and 10 case series met the inclusion criteria, totaling 108 patients. The case series were meta-analyzed. Mean age was 56.4 years old, 59% were men, and 15% were kidney transplant recipients. Fat malabsorption (88%) was the most commonly attributed cause of oxalate nephropathy, followed by excessive dietary oxalate consumption (20%). The mean baseline serum creatinine was 1.3 mg/dl and peaked at 4.6 mg/dl. Proteinuria, hematuria, and urinary crystals was reported in 69%, 32%, and 26% of patients, respectively. Mean 24-hour urinary oxalate excretion was 85.4 mg/d. In addition to universal oxalate crystal deposition in tubules and/or interstitium, kidney biopsy findings included acute tubular injury (71%), tubular damage and atrophy (69%), and interstitial mononuclear cell infiltration (72%); 55% of patients required dialysis. None had complete recovery, 42% had partial recovery, and 58% remained dialysis-dependent. Thirty-three percent of patients died.
conclusionSecondary oxalate nephropathy is a rare but potentially devastating condition. Renal replacement therapy is required in >50% of patients, and most patients remain dialysis-dependent. Studies are needed for effective preventive and treatment strategies in high-risk patients with hyperoxaluria-enabling conditions.
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