Evidence map›Paper›PMID 30450462›Full record

ArticleKidney international reports2018

Kareshma Asharam, Rajendra Bhimma, Victor A David, Hoosen M Coovadia, Wenkosi P Qulu, Thajasvarie Naicker, Christopher E Gillies, Virginia Vega-Warner, Randall C Johnson, Sophie Limou and 4 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Kareshma AsharamUniversity of KwaZulu-Natal, Durban, South Africa.
Rajendra BhimmaUniversity of KwaZulu-Natal, Durban, South Africa.
Victor A DavidBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
Hoosen M CoovadiaUniversity of KwaZulu-Natal, Durban, South Africa.
Wenkosi P QuluUniversity of KwaZulu-Natal, Durban, South Africa.
Thajasvarie NaickerUniversity of KwaZulu-Natal, Durban, South Africa.
Christopher E GilliesDepartment of Pediatrics-Nephrology; University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
Virginia Vega-WarnerDepartment of Pediatrics-Nephrology; University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
Randall C JohnsonAdvanced Biomedical Computing Center, Frederick National Laboratory, Frederick, Maryland, USA.
Sophie LimouBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, USA.
Jeffrey B KoppKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA.
Mathew SampsonDepartment of Pediatrics-Nephrology; University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
George W NelsonAdvanced Biomedical Computing Center, Frederick National Laboratory, Frederick, Maryland, USA.
Cheryl A WinklerBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, USA.
University of KwaZulu-Natal · ZAUniversity of Michigan–Ann Arbor · USCenter for Cancer Research · USLeidos (United States) · USNational Cancer Institute · USNational Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Focal Segmental Glomerulosclerosis: Genetics & MechanismsZIADK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 2009 to 2024
$15.7M
Genetics of Renal Disease in African AmericansZIABC010022 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINKLER, CHERYL · 2009 to 2022
$8.9M
6 · The paper itself

Abstract

introductionIn South Africa (SA), steroid-resistant nephrotic syndrome (SRNS) is more frequent in black than in Indian children.

methodsSeeking a genetic basis for this disparity, we enrolled 33 Indian and 31 black children with steroid-sensitive nephrotic syndrome (SSNS) and SRNS from KwaZulu-Natal, SA; SRNS children underwent kidney biopsy. We sequenced

resultsHomozygosity for

conclusion

Indexed as

APOL1CD2APFSGSnephrotic syndromeNPHS2steroid resistance

Identifiers

PMID30450462
PMCPMC6224675
OpenAlexW2883076975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.