Evidence map›Paper›PMID 30450454›Full record

ArticleKidney international reports2018

Sleep-Disordered Breathing and Prevalent Albuminuria in Hispanics/Latinos.

Ana C Ricardo, Jinsong Chen, Manpreet Singh, Gerardo Heiss, Leopoldo Raij, Alberto Ramos, Susan Redline, Sylvia E Rosas, Neomi Shah, Daniela Sotres-Alvarez and 3 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Give the Kidneys a Good Night of Sleep.Annals of the American Thoracic Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Ana C RicardoDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
Jinsong ChenDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
Manpreet SinghDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
Gerardo HeissDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Leopoldo RaijDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Alberto RamosDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Susan RedlineDepartments of Medicine and Neurology, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Sylvia E RosasJoslin Diabetes Center and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Neomi ShahDepartment of Medicine, Montefiore Medical Center, New York, New York.
Daniela Sotres-AlvarezCollaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
Phyllis ZeeDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Martha DaviglusInstitute for Minority Health Research, University of Illinois, Chicago, Illinois, USA.
James P LashDepartment of Medicine, University of Illinois, Chicago, Illinois, USA.
University of Illinois Chicago · USUniversity of Miami · USUniversity of North Carolina at Chapel Hill · USBrigham and Women's Hospital · USJoslin Diabetes Center · USMontefiore Medical Center · USNorthwestern University · USUniversity of Illinois Urbana-Champaign · US

Funding

Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
Health Disparities in Chronic Kidney Disease Mentoring ProgramK24DK092290 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LASH, JAMES P. · 2012 to 2022
$1.9M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
Gender Disparities and Vascular Function in Chronic Kidney Disease OutcomesK23DK094829 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RICARDO, ANA CATHERINE · 2013 to 2017
$800k
Exploring Sleep in Neurocognitive Aging and Alzheimer's Research (eSANAR)R21AG056952 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RAMOS, ALBERTO RAFAEL · 2017 to 2018
$411k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NIDDK NIH HHS K23 DK094829NIDDK NIH HHS K24 DK092290
6 · The paper itself

Abstract

introductionAlthough sleep-disordered breathing has been found to be associated with higher urine albumin excretion, this association has not been evaluated in Hispanic/Latino populations, which experience a high burden of end-stage renal disease compared with non-Hispanics. We evaluated the association of sleep-disordered breathing with prevalent albuminuria among US Hispanics/Latinos.

methodsThis was a cross-sectional study of baseline data from participants in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a population-based study that enrolled 16,415 adults in 4 US communities. Sleep-disordered breathing was assessed using a home sleep apnea monitor for overnight recording and was defined using 3 thresholds of the apnea-hypopnea index (AHI; 3% desaturation): ≥5, ≥15, and ≥30. Albuminuria was defined as a urine albumin-to-creatinine ratio of ≥30 mg/g.

resultsThere were 12,572 participants with complete data available for analysis. The age- and sex-adjusted prevalence of albuminuria was 9.1%. Mean age was 41 years, and 48% were men. Age- and sex-adjusted prevalence of sleep-disordered breathing was higher among individuals with albuminuria compared with those without albuminuria (36% vs. 25% had AHI ≥5, 18% vs. 9% had AHI ≥15, and 9% vs. 4% had AHI ≥30). In multivariable logistic regression analyses, AHIs ≥5, ≥15, and ≥30 were associated with greater odds of albuminuria compared with those with AHIs <5, <15, and <30 (odds ratio [OR] 1.42, 95% confidence interval [CI]: 1.14-1.76; OR: 1.71, 95% CI: 1.33-2.20; and OR 1.93, 95% CI 1.34-2.79), respectively. This association varied by Hispanic/Latino background group.

conclusionIn US Hispanic/Latinos, sleep-disordered breathing was independently associated with higher odds of prevalent albuminuria.

Indexed as

chronic kidney diseaseHispanics/Latinossleep apnea

Identifiers

PMID30450454
PMCPMC6224780
OpenAlexW2810560155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.