Evidence map›Paper›PMID 30450409›Full record

ReviewLaryngoscope investigative otolaryngology2018

Tobacco carcinogen research to aid understanding of cancer risk and influence policy.

Hitesh Singhavi, Jasjit S Ahluwalia, Irina Stepanov, Prakash C Gupta, Vikram Gota, Pankaj Chaturvedi, Samir S Khariwala

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. A review of tobacco abuse and its epidemiological consequences.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Hitesh SinghaviFrom the Tata Memorial Centre Mumbai India.
Jasjit S AhluwaliaThe School of Public Health Brown University Providence Rhode Island U.S.A.
Irina Stepanovchool of Public Health Minneapolis Minnesota U.S.A.
Prakash C GuptaHealis-Sekhsaria Institute for Public Health Minneapolis Minnesota U.S.A.
Vikram GotaFrom the Tata Memorial Centre Mumbai India.
Pankaj ChaturvediFrom the Tata Memorial Centre Mumbai India.
Samir S KhariwalaDepartment of Otolaryngology-Head and Neck Surgery University of Minnesota Minneapolis Minnesota U.S.A.ORCID https://orcid.org/0000-0002-5579-4990
Tata Memorial Hospital · INHealis Sekhsaria Institute For Public Health · INMinnesota Department of Health · USRhode Island Department of Health · USUniversity of Minnesota · US

Funding

Analytical capacity building for the study of tobacco carcinogen exposures in IndiaR01TW010651 · FIC · UNIVERSITY OF MINNESOTA · PI CHATURVEDI, PANKAJ, KHARIWALA, SAMIR S · 2017 to 2021
$1.4M
Tobacco carcinogens as markers of exposure, carcinogenesis and risk in oral canceK23DE023572 · NIDCR · UNIVERSITY OF MINNESOTA · PI KHARIWALA, SAMIR S · 2013 to 2017
$681k
FIC NIH HHS R01 TW010651NIDCR NIH HHS K23 DE023572
6 · The paper itself

Abstract

Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users' risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. LEVEL OF EVIDENCE: 4.

Indexed as

carcinogenDNA adductHead and neck cancerLevel of Evidencenitrosaminestobacco

Identifiers

PMID30450409
PMCPMC6209619
OpenAlexW2895524957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.