Evidence map›Paper›PMID 30450387›Full record

ReviewNeurobiology of stress2018

Leveraging translational neuroscience to inform early intervention and addiction prevention for children exposed to early life stress.

Leslie E Roos, Sarah Horn, Elliot T Berkman, Katherine Pears, Philip A Fisher

Open access · goldAbstract readReview
In one paragraph

Review in Neurobiology of stress, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Commentary on the Culture of Prevention.Prevention science : the official journal of the Society for Prevention Research · 2021
    Article
  5. Mapping sign-tracking and goal-tracking onto human behaviors.Neuroscience and biobehavioral reviews · 2020
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Leslie E RoosUniversity of Oregon, Department of Psychology, Eugene, OR, United States.
Sarah HornUniversity of Oregon, Department of Psychology, Eugene, OR, United States.
Elliot T BerkmanUniversity of Oregon, Department of Psychology, Eugene, OR, United States.
Katherine PearsOregon Social Learning Center, Eugene, OR, United States.
Philip A FisherUniversity of Oregon, Department of Psychology, Eugene, OR, United States.
University of Oregon · USOregon Social Learning Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substance use and addiction are disproportionately experienced by individuals with a history of exposure to early life stress (ELS), such as maltreatment, domestic violence and parent psychopathology. Unfortunately, extant interventions have mixed effectiveness at improving outcome trajectories for ELS-exposed children, who are often underserved by evidenced-based programs. Here, we employ a translational neuroscience framework to delineate how neuroscience can deepen our understanding of ELS-linked alterations in children's function to inform the development of more targeted, effective early intervention and addiction prevention programs. Candidate neural pathways altered by ELS and linked to addiction are described across sensory, affective, motivational, and executive function domains. Next, we provide an example of the application of translational neuroscience principles in a family of early interventions (i.e. Multidimensional Treatment Foster Care - Preschool, Kids in Transition to School) focused on improving self-regulation in ELS-exposed children. Future directions and areas of unmet need in intervention research detail the significant potential of translational neuroscience to advance interventionists' ability to support positive adjustment in ELS-exposed children and prevent harmful addiction outcomes.

Indexed as

AddictionAdversityEarly life stressInterventionPreventionTranslational neuroscience

Identifiers

PMID30450387
PMCPMC6236514
OpenAlexW2898599883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.