Evidence map›Paper›PMID 30450304›Full record

ArticleInternational journal of ophthalmology2018

Effect of green flickering light on myopia development and expression of M1 muscarinic acetylcholine receptor in guinea pigs.

Yuan Tao, Xiao-Li Li, Li-Yuan Sun, Yu-Hua Wei, Xiao-Ting Yu, Hong Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Influence of light on myopia-a review.International journal of ophthalmology · 2026
    Review
  2. Review
  3. Topical review: Potential mechanisms of atropine for myopia control.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Review
  4. Article
  5. [Relationship between Myopia and Light Exposure].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021
    Review
  6. Muscarinic Acetylcholine Receptors in the Retina-Therapeutic Implications.International journal of molecular sciences · 2021
    Review
  7. IMI 2021 Yearly Digest.Investigative ophthalmology & visual science · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuan TaoDepartment of Ophthalmology, the Second People's Hospital of Jinan City, Jinan 250001, Shandong Province, China.
Xiao-Li LiDepartment of Laboratory Medicine, Qilu Hospital of Shandong University, Jinan 250001, Shandong Province, China.
Li-Yuan SunDepartment of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250001, Shandong Province, China.
Yu-Hua WeiDepartment of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250001, Shandong Province, China.
Xiao-Ting YuDepartment of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250001, Shandong Province, China.
Hong WangDepartment of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250001, Shandong Province, China.
Qilu Hospital of Shandong University · CNFourth People’s Hospital of Jinan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effects of green flickering light on refractive development and expression of muscarinic acetylcholine receptor (mAChR) M1 in the eyes of guinea pigs.

methodsThirty guinea pigs (15-20 days old) were randomly divided into three groups (

resultsThere was a remarkable reduction in refractive error and increase in axial length after 8-weeks' green flickering light stimulation (

conclusionMyopia can be induced by 8 weeks' green flickering light exposure in the animal model. M1 receptor may be involved causally or protectively in myopia development.

Indexed as

green flashing lightguinea pigsmuscarinic acetylcholine 1 receptormyopia model

Identifiers

PMID30450304
PMCPMC6232333
OpenAlexW2911705942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.