Evidence map›Paper›PMID 30450266›Full record

ArticlePLoS currents2018

Estimation of Pneumonic Plague Transmission in Madagascar, August-November 2017.

Maimuna S Majumder, Emily L Cohn, Mauricio Santillana, John S Brownstein

Abstract read
In one paragraph

Article in PLoS currents, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Deliberate release: Plague - A review.Journal of biosafety and biosecurity · 2020
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maimuna S MajumderComputational Epidemiology Group, Division of Emergency Medicine, Boston Children's Hospital, Boston, MA, United States; Institute for Data, Systems, and Society (IDSS), Massachusetts Institute of Technology, Cambridge, MA, United States.
Emily L CohnComputational Epidemiology Group, Division of Emergency Medicine, Boston Children's Hospital, Boston, MA, United States; Department of Pediatrics, Harvard Medical School, Boston, MA, United States.
Mauricio SantillanaDepartment of Pediatrics, Harvard Medical School, Boston, MA, United States.
John S BrownsteinComputational Epidemiology Group, Division of Emergency Medicine, Boston Children's Hospital, Boston, MA, United States; Department of Pediatrics, Harvard Medical School, Boston Children's Hospital, Boston, MA, United States.

Funding

A Platform for Modeling the Global Impact of Climate Change on Infectious DiseaseR01LM010812 · NLM · BOSTON CHILDREN'S HOSPITAL · PI BROWNSTEIN, JOHN S. · 2010 to 2015
$2.5M
NLM NIH HHS R01 LM010812
6 · The paper itself

Abstract

introductionBetween August and November 2017, Madagascar reported nearly 2500 cases of plague; the vast majority of these cases were pneumonic, resulting in early exponential growth due to person-to-person transmission. Though plague is endemic in Madagascar, cases are usually bubonic and thus result in considerably smaller annual caseloads than those observed from August-November 2017.

methodsIn this study, we consider the transmission dynamics of pneumonic plague in Madagascar during this time period, as well as the role of control strategies that were deployed to curb the outbreak and their effectiveness.

resultsWhen using data from the beginning of the outbreak through late November 2017, our estimates for the basic reproduction number range from 1.6 to 3.6, with a mean of 2.4. We also find two distinctive periods of "control", which coincide with critical on-the-ground interventions, including contact tracing and delivery of antibiotics, among others. DISCUSSION: Given these results, we conclude that existing interventions remain effective against plague in Madagascar, despite the atypical size and spread of this particular outbreak.

Indexed as

Madagascarplague

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.