Evidence map›Paper›PMID 30450237›Full record

ArticleJournal of thoracic disease2018

Complications related to endoscopic lung volume reduction for emphysema with endobronchial valves: results of a multicenter study.

Alfonso Fiorelli, Antonio D'Andrilli, Michela Bezzi, Mohsen Ibrahim, Marco Anile, Daniele Diso, Giacomo Cusumano, Alberto Terminella, Valentina Luzzi, Margherita Innocenti and 16 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Guideline
  2. Lung volume reduction surgeryThe European respiratory journal · 2023
    Trial
  3. Article
  4. Bronchoscopic endobronchial valves.Breathe (Sheffield, England) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  14. Article
  15. Review
  16. Airway granulation response to lung-implantable medical devices: a concise overview.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 5 institutions in 1 country.

Alfonso FiorelliThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Antonio D'AndrilliThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Michela BezziInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Mohsen IbrahimThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Marco AnileThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Daniele DisoThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Giacomo CusumanoThoracic Surgery Unit, Policlinico Vittorio Emanuele Hospital, Catania, Italy.
Alberto TerminellaThoracic Surgery Unit, Policlinico Vittorio Emanuele Hospital, Catania, Italy.
Valentina LuzziInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Margherita InnocentiInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Mauro NovaliInterventional Pneumology Unit, Spedili Civili Brescia, Brescia, Italy.
Emanuele CarelliThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Chiara FredaThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Giovanni NataleThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Valentina PeritoreThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Camilla PoggiThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Giuseppe FaillaInterventional Pneumology Unit, Ospedale Civico Palermo, Palermo, Italy.
Marco BasileInterventional Pneumology Unit, Ospedale Civico Palermo, Palermo, Italy.
Emilia MazzuccaInterventional Pneumology Unit, Ospedale Civico Palermo, Palermo, Italy.
Serena ConfortiThoracic Surgery Unit, Ospedale Niguarda, Milan, Italy.
Nicola SerraDepartment of Pediatrics, University Federico II of Naples, Naples, Italy.
Massimo TorreThoracic Surgery Unit, Ospedale Niguarda, Milan, Italy.
Federico VenutaThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Erino Angelo RendinaThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Mario SantiniThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Claudio AndreettiThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Azienda Ospedaliera Sant'Andrea · ITUniversity of Campania "Luigi Vanvitelli" · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite bronchoscopic lung volume reduction (BLVR) with valves is a minimally invasive treatment for emphysema, it can associate with some complications. We aimed at evaluating the rate and type of complications related to valve treatment and their impact on clinical outcomes.

methodsIt is a retrospective multicenter study including all consecutive patients with severe heterogeneous emphysema undergoing BLVR with endobronchial valve treatment and developed any complications related to this procedure. The type of complication, the time of onset, the treatment required and the out-come were evaluated. Response to treatment was assessed according to the minimal clinically important difference (MCID) as follows: an improvement of ≥15% in forced expiratory volume in one second (FEV

resultsOne hundred and seven out of 423 (25.3%) treated patients had complications related to valve treatment including pneumothorax (17.3%); pneumonia (1.7%), chronic obstructive pulmonary disease (COPD) exacerbation (0.9%), respiratory failure (1.4%), valve migration (2.1%), and hemoptysis (1.9%). In all cases complications resolved with appropriate treatment including removal of valves in 21/107 cases (19.6%). Patients with TLVR ≥350 mL (n=64)

conclusionsValve treatment is a safe and reversible procedure. The presence of complications seems not to have a significant impact on clinical outcome in patients with lobar atelectasis. Due to poor clinical conditions and possible complications, BLVR should be performed in high volume centers with a multidisciplinary approach.

Indexed as

bronchoscopic lung volume reduction (BLVR)emphysemaZephyr endo-bronchial valves

Identifiers

PMID30450237
PMCPMC6204336
OpenAlexW2811511468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.