Evidence map›Paper›PMID 30450141›Full record

ArticleThe open microbiology journal2018

First Detection of

Valentina Feodorova, Edgar Sultanakhmedov, Yury Saltykov, Sergey Zaitsev, Sergey Utz, Michael Corbel, Charlotte Gaydos, Thomas Quinn, Vladimir Motin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The open microbiology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Evaluation ofJournal of tropical medicine · 2023
    Article
  3. Molecular Genotyping ofArchives of Razi Institute · 2022
    Article
  4. Seminal pro-inflammatory cytokines and pH are affected byCentral-European journal of immunology · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Valentina FeodorovaLaboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology, Branch in Saratov, Ap. 6, the 53 Strelkovoi Divisii Street, Saratov, 410028, Russia.
Edgar SultanakhmedovDepartment for Skin Diseases, Saratov State Medical University, 22, Proviantskaya Street, Saratov, 410028, Russia.
Yury SaltykovLaboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology, Branch in Saratov, Ap. 6, the 53 Strelkovoi Divisii Street, Saratov, 410028, Russia.
Sergey ZaitsevLaboratory for Molecular Biology and NanoBiotechnology, Federal Research Center for Virology and Microbiology, Branch in Saratov, Ap. 6, the 53 Strelkovoi Divisii Street, Saratov, 410028, Russia.
Sergey UtzDepartment for Skin Diseases, Saratov State Medical University, 22, Proviantskaya Street, Saratov, 410028, Russia.
Michael CorbelDepartment of Bacteriology, The National Institute for Biological Standards and Control (NIBSC), Potters Bar, EN6 3QG, UK.
Charlotte GaydosDivision of Infectious Diseases, Johns Hopkins University School of Medicine, 855 N. Wolfe Street, Rangos Bldg, Suite 530, Baltimore, MD 21205, USA.
Thomas QuinnDivision of Infectious Diseases, Johns Hopkins University School of Medicine, 855 N. Wolfe Street, Rangos Bldg, Suite 530, Baltimore, MD 21205, USA.
Vladimir MotinDepartment of Pathology & Immunology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0609, USA.
Saratov State Medical University · RUNational Institute for Biological Standards and Control · GBNational Institutes of Health · USThe University of Texas Medical Branch at Galveston · US

Funding

TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Yukari C Manabe, Susan Anne Tuddenham · 2007 to 2026
$34.6M
Immunopathogenesis Of Chlamydia trachomatis InfectionZIAAI000358 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI QUINN, THOMAS · 2009 to 2022
$7.0M
NIBIB NIH HHS U54 EB007958
6 · The paper itself

Abstract

backgroundChronic asymptomatic chlamydial genital infection caused by the wild-type of

objectiveThe study aimed to investigate whether nvCT may be a possible cause of infertility in a couple undergoing

methodClinical specimens from both genital (urethra and cervix) and extra-genital sites (pharynx, conjunctive, blood) of a couple who experienced multiple unsuccessful attempts at pregnancy by natural fertilization and IVF procedures were analyzed before and after antibiotic therapy. Both partners had neither somatic nor endocrinal abnormality nor any clinically apparent genital manifestations of

resultsBefore antibiotic therapy all the samples of the Female Partner (FP) contained DNA of only the nvCT. After antibiotic therapy, additionally, DNA of wtCT of genovars E and D was detected in specimens from her conjunctiva and oropharynx. All samples of the Male Partner (MP) revealed co-infection of nvCT and wtCT. Identical SNP within the variable region 4 (VD4) of the

conclusionInfertility in this couple may have been caused by chronic asymptomatic and persistent nvCT-associated infection that was complicated by re-infection later with wtCT. This study illustrates the importance of including detection methods for nvCT strains in the investigation of infertility cases.

Indexed as

Chlamydia trachomatisCo-infectionDetection methodsExtra-genital siteInfertilityNovel Swedish strain

Identifiers

PMID30450141
PMCPMC6198409
OpenAlexW2897632679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.