Evidence map›Paper›PMID 30450027›Full record

ArticleJournal of Korean medical science2018

Ye-Hwan Kim, Young Joon Byun, Won Tae Kim, Pildu Jeong, Chunri Yan, Ho Won Kang, Yong-June Kim, Sang-Cheol Lee, Sung-Kwon Moon, Yung-Hyun Choi and 2 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. CDC6 is up-regulated and a poor prognostic signature in glioblastoma multiforme.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  12. Article
  13. CDC6 is a possible biomarker for hepatocellular carcinoma.International journal of clinical and experimental pathology · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ye-Hwan KimDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-8676-7119
Young Joon ByunDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0003-0528-1502
Won Tae KimDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-7482-4550
Pildu JeongDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-5602-5376
Chunri YanDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-3043-6687
Ho Won KangDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-8164-4427
Yong-June KimDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0001-7638-7174
Sang-Cheol LeeDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-4163-2210
Sung-Kwon MoonDepartment of Food and Nutrition, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0000-0002-4514-3457
Yung-Hyun ChoiDepartment of Biochemistry, Dongeui University College of Oriental Medicine, Busan, Korea.ORCID https://orcid.org/0000-0002-1454-3124
Seok Joong YunDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0001-7737-4746
Wun-Jae KimDepartment of Urology, Chungbuk National University, College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-8060-8926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCell division cycle 6 (CDC6) is an essential regulator of DNA replication and plays important roles in the activation and maintenance of the checkpoint mechanisms in the cell cycle. CDC6 has been associated with oncogenic activities in human cancers; however, the clinical significance of CDC6 in prostate cancer (PCa) remains unclear. Therefore, we investigated whether the

methodsThe study subjects included 121 PCa patients and 66 age-matched benign prostatic hyperplasia (BPH) patients.

results

conclusion

Indexed as

AdultAgedArea Under CurveCase-Control StudiesCell Cycle ProteinsHumansLogistic ModelsLymphatic MetastasisMaleMiddle AgedNeoplasm GradingNeoplasm StagingNuclear ProteinsOdds RatioProstate-Specific AntigenProstatic HyperplasiaCDC6 protein, humanCell Cycle ProteinsNuclear ProteinsProstate-Specific AntigenRNA, MessengerCDC6Gene ExpressionImmunohistochemical StainingProstatic Neoplasms

Identifiers

PMID30450027
PMCPMC6236078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.