ArticleMaterials today (Kidlington, England)2018
Three-dimensional Printing of Multilayered Tissue Engineering Scaffolds.
Article in Materials today (Kidlington, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed.
- 3D bioprinting technologies and biomaterial-based scaffolds for wound healing: Insights into decellularized tissue-derived bioinks.Regenerative therapy · 2026Review
- Multifunctional Metal-Coordinated Hydrogels: Controlled Synthesis and Advances in Anti-Inflammatory, Anticancer, and Antibacterial Applications.ACS omega · 2026Review
- Engineering Strain-Stiffening Granular Hydrogels for 3D-Printed Tissue-Mimicry.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Biomaterials in organoid research: current state and future directions.Frontiers in bioengineering and biotechnology · 2026Review
- Three-Dimensional Printed Hybrid Scaffolds with Layered Polycaprolactone/Nanosized Smectic Clay Nanocomposite and Chitosan/Collagen/Demineralized Bone Powder Hydrogels Targeting Osteochondral Tissue Engineering.Journal of functional biomaterials · 2025Article
- [Research advances in three-dimensional bioprinted wound dressings].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Review
- 3D Printing for Tissue Engineering: Printing Techniques, Biomaterials, Challenges, and the Emerging Role of 4D Bioprinting.Bioengineering (Basel, Switzerland) · 2025Review
- Computational optimization of 3D printed bone scaffolds using orthogonal array-driven FEA and neural network modeling.Scientific reports · 2025Article
- Pre-Loading of Cells via Vapor Sublimation and the Deposition Polymerization Process with a 3D Porous Scaffold for Cell Cultures.ACS biomaterials science & engineering · 2025Article
- Bioactive Inorganic Materials for Innervated Multi-Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Gradient scaffolds in bone-soft tissue interface engineering: Structural characteristics, fabrication techniques, and emerging trends.Journal of orthopaedic translation · 2025Review
- Bioprinting of a multi-composition array to mimic intra-tumor heterogeneity of glioblastoma for drug evaluation.Microsystems & nanoengineering · 2024Article
- 3D Printing-Based Hydrogel Dressings for Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- The cutting-edge progress in bioprinting for biomedicine: principles, applications, and future perspectives.MedComm · 2024Review
- Review on Engineering of Bone Scaffolds Using Conventional and Additive Manufacturing Technologies.3D printing and additive manufacturing · 2024Review
- Zonal Patterning of Extracellular Matrix and Stromal Cell Populations Along a Perfusable Cellular Microchannel.bioRxiv : the preprint server for biology · 2024Article
- Vat photopolymerization printing of functionalized hydrogels on commercial contact lenses.Scientific reports · 2024Article
- Seamless Integration of Conducting Hydrogels in Daily Life: From Preparation to Wearable Application.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- New insight into biodegradable macropore filler on tuning mechanical properties and bone tissue ingrowth in sparingly dissolvable bioceramic scaffolds.Materials today. Bio · 2024Article
- Peptide-Based Biomaterials for Bone and Cartilage Regeneration.Biomedicines · 2024Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The field of tissue engineering has produced new therapies for the repair of damaged tissues and organs, utilizing biomimetic scaffolds that mirror the mechanical and biological properties of host tissue. The emergence of three-dimensional printing (3DP) technologies has enabled the fabrication of highly complex scaffolds which offer a more accurate replication of native tissue properties and architecture than previously possible. Of strong interest to tissue engineers is the construction of multilayered scaffolds that target distinct regions of complex tissues. Musculoskeletal and dental tissues in particular, such as the osteochondral unit and periodontal complex, are composed of multiple interfacing tissue types, and thus benefit from the usage of multilayered scaffold fabrication. Traditional 3DP technologies such as extrusion printing and selective laser sintering have been used for the construction of scaffolds with gradient architectures and mixed material compositions. Additionally, emerging bioprinting strategies have been used for the direct printing and spatial patterning of cells and chemical factors, capturing the complex organization found in the body. To better replicate the varied and gradated properties of larger tissues, researchers have created scaffolds composed of multiple materials spanning natural polymers, synthetic polymers, and ceramics. By utilizing high precision 3DP techniques and judicious material selection, scaffolds can thus be designed to address the regeneration of previously challenging musculoskeletal, dental, and other heterogeneous target tissues. These multilayered 3DP strategies show great promise in the future of tissue engineering.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.