Evidence map›Paper›PMID 30449799›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Community-acquired Disseminated Exophiala dermatitidis Mycosis with Necrotizing Fasciitis in Chronic Graft-versus-host Disease.

Eiichi Sato, Atsushi Togawa, Michio Masaki, Akihiko Shirahashi, Midori Kumagawa, Yasumasa Kawano, Hiroyasu Ishikura, Yuri Yamashiro, Satoshi Takagi, Hiromi To and 7 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. IDCases · 2022
    Article
  4. Antimicrobial agents and chemotherapy · 2020
    Article
  5. The skin and soft tissue infections in hematological patients.Current opinion in infectious diseases · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Eiichi SatoDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Atsushi TogawaDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Michio MasakiDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Akihiko ShirahashiDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Midori KumagawaDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Yasumasa KawanoDepartment of Emergency and Critical Care Medicine, Fukuoka University Hospital, Japan.
Hiroyasu IshikuraDepartment of Emergency and Critical Care Medicine, Fukuoka University Hospital, Japan.
Yuri YamashiroDepartment of Plastic and Reconstructive Surgery, Fukuoka University Hospital, Japan.
Satoshi TakagiDepartment of Plastic and Reconstructive Surgery, Fukuoka University Hospital, Japan.
Hiromi ToDepartment of Clinical Laboratory Medicine, Fukuoka University Hospital, Japan.
Katsumi KobataDepartment of Pathology, Fukuoka University Hospital, Japan.
Morishige TakeshitaDepartment of Pathology, Fukuoka University Hospital, Japan.
Koji KusabaDepartment of Laboratory Medicine, Saga University Hospital, Japan.
Eisaburo SueokaDepartment of Laboratory Medicine, Saga University Hospital, Japan.
Kazuo TamuraDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Yasushi TakamatsuDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Tohru TakataDivision of Medical Oncology, Hematology, and Infectious Diseases, Department of Internal Medicine, Fukuoka University Hospital, Japan.
Fukuoka University Hospital · JPSaga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of systemic phaeohyphomycosis by Exophiala dermatitidis (E. dermatitidis) with chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT). The patient had been taking oral corticosteroids for years to control the GVHD. Yeast-like fungi were identified in a blood culture, so treatment with micafungin (150 mg/day) was begun, with no improvement. The patient passed away on hospital Day 12. A sequence analysis of rRNA revealed the isolate to be E. dermatitidis. This report brings attention to an emerging mycosis of community-acquired Exophiala species infection in the very-late phase after allogenic HSCT in patients with chronic GVHD.

Indexed as

Chronic DiseaseExophialaFasciitis, NecrotizingFemaleGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansPhaeohyphomycosisYoung Adultacute myeloid leukemiachronic graft versus host disease (GVHD)Exophiala dermatitidisimmunosuppressive drugnecrotizing fasciitisphaeohyphomycosis

Identifiers

PMID30449799
PMCPMC6465022
OpenAlexW2901296449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.