Evidence map›Paper›PMID 30449785›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Severe Chronic Inflammatory Demyelinating Polyneuropathy Ameliorated following High-dose (3 g/kg) Intravenous Immunoglobulin Therapy.

Yusuke Seino, Takumi Nakamura, Mie Hirohata, Takeshi Kawarabayashi, Toshimi Okushima, Mikio Shoji

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yusuke SeinoDepartment of Neurology, Hirosaki University Graduate School of Medicine, Japan.
Takumi NakamuraDepartment of Neurology, Hirosaki University Graduate School of Medicine, Japan.
Mie HirohataDepartment of Neurology, Hirosaki University Graduate School of Medicine, Japan.
Takeshi KawarabayashiDepartment of Neurology, Hirosaki University Graduate School of Medicine, Japan.
Toshimi OkushimaDepartment of Neurology, Hachinohe City Hospital, Japan.
Mikio ShojiDepartment of Neurology, Hirosaki University Graduate School of Medicine, Japan.
Hirosaki University · JPHachinohe Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 53-year-old woman with severe chronic inflammatory demyelinating polyneuropathy (CIDP) who developed progressive tetraplegia with respiratory failure despite receiving a standard dose of intravenous immunoglobulin therapy (IVIg), steroid pulse therapy, plasma exchange, and cyclosporine. We administered high-dose IVIg (3 g/kg; 0.6 g/kg/day for 5 consecutive days at monthly intervals). The patient's muscle weakness gradually improved after IVIg. She recovered completely 2 years after the onset of symptoms. The effects of IVIg treatment in individuals with CIDP may vary in each patient. In patients with refractory CIDP receiving standard-dose IVIg, repeated high-dose IVIg treatment can be considered.

Indexed as

Dose-Response Relationship, DrugFemaleHumansImmunoglobulins, IntravenousImmunologic FactorsMiddle AgedPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingSeverity of Illness IndexImmunoglobulins, IntravenousImmunologic Factorschronic inflammatory demyelinating polyneuropathy (CIDP)high-dose intravenous immunoglobulin therapy (IVIg)pentaplegiarespiratory failure

Identifiers

PMID30449785
PMCPMC6465009
OpenAlexW2900644253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.