Evidence map›Paper›PMID 30449666›Full record

ArticleCurrent biology : CB2018

Whole-Brain Calcium Imaging during Physiological Vestibular Stimulation in Larval Zebrafish.

Geoffrey Migault, Thijs L van der Plas, Hugo Trentesaux, Thomas Panier, Raphaël Candelier, Rémi Proville, Bernhard Englitz, Georges Debrégeas, Volker Bormuth

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 111 citations in OpenAlex.

  1. Plag1 Regulates Sensorimotor Modulation in Zebrafish.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026
    Article
  2. Heart rate control by listening to light.Nature communications · 2026
    Article
  3. Critical period plasticity enables credit assignment.bioRxiv : the preprint server for biology · 2026
    Article
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  15. Brain-Wide Impacts of Sedation on Spontaneous Activity and Auditory Processing in Larval Zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  16. Review
  17. Habituation learning: insights from zebrafish larvae.Frontiers in molecular neuroscience · 2025
    Review
  18. Review
  19. Defects in Exosome Biogenesis Are Associated with Sensorimotor Defects in ZebrafishThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  20. Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Geoffrey MigaultLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France.
Thijs L van der PlasLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Donders Centre for Neuroscience, Department of Neurophysiology, Radboud University, Nijmegen, the Netherlands.
Hugo TrentesauxLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France.
Thomas PanierLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France.
Raphaël CandelierLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France.
Rémi ProvilleNeurocentre Magendie, Physiopathologie de la Plasticité Neuronale, INSERM, U1215, 33077 Bordeaux Cedex, France.
Bernhard EnglitzDonders Centre for Neuroscience, Department of Neurophysiology, Radboud University, Nijmegen, the Netherlands.
Georges DebrégeasLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France.
Volker BormuthLaboratoire Jean Perrin, Sorbonne Université, UMR 8237, 75005 Paris, France; Laboratoire Jean Perrin, CNRS, UMR 8237, 75005 Paris, France. Electronic address: volker.bormuth@upmc.fr.
Centre National de la Recherche Scientifique · FRRadboud University Nijmegen · NLNeurocentre Magendie · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vestibular apparatus provides animals with postural and movement-related information that is essential to adequately execute numerous sensorimotor tasks. In order to activate this sensory system in a physiological manner, one needs to macroscopically rotate or translate the animal's head, which in turn renders simultaneous neural recordings highly challenging. Here we report on a novel miniaturized, light-sheet microscope that can be dynamically co-rotated with a head-restrained zebrafish larva, enabling controlled vestibular stimulation. The mechanical rigidity of the microscope allows one to perform whole-brain functional imaging with state-of-the-art resolution and signal-to-noise ratio while imposing up to 25° in angular position and 6,000°/s

Indexed as

AnimalsBrainFunctional NeuroimagingMicroscopyVestibule, LabyrinthZebrafish4D data visualizationcalcium imagingfunctional whole-brain imaginglight-sheet microscopymicroscopy developmentregression analysissensory processingvestibular systemzebrafish

Identifiers

PMID30449666
PMCPMC6288061
OpenAlexW2949794077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.