ArticleGenetics, selection, evolution : GSE2018
Genome-wide patterns of homozygosity provide clues about the population history and adaptation of goats.
Article in Genetics, selection, evolution : GSE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Runs of homozygosity reveal population dynamics and selection across global cattle.Journal of animal science and biotechnology · 2026Article
- Inferring Domestic Goat Demographic History Through Ancient Genome Imputation.Genome biology and evolution · 2025Article
- A comprehensive genome-wide analysis for signatures of selection in goat (genus Capra) revealed new candidate genes for environmental adaptation and productive traits.BMC genomics · 2025Article
- Article
- Runs of Homozygosity Preliminary Investigation in Pig Breeds.Animals : an open access journal from MDPI · 2025Article
- Genome-wide landscape of genetic diversity, runs of homozygosity, and runs of heterozygosity in five Alpine and Mediterranean goat breeds.Journal of animal science and biotechnology · 2025Article
- Article
- Examination of homozygosity runs and selection signatures in native goat breeds of Henan, China.BMC genomics · 2024Article
- Investigating the footprint of post-domestication dispersal on the diversity of modern European, African and Asian goats.Genetics, selection, evolution : GSE · 2024Article
- Article
- Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat.Animals : an open access journal from MDPI · 2024Article
- Genome-Wide Detection for Runs of Homozygosity in Baoshan Pigs Using Whole Genome Resequencing.Genes · 2024Article
- Genome-wide detection of selection signatures in Jianli pigs reveals novel cis-regulatory haplotype in EDNRB associated with two-end black coat color.BMC genomics · 2024Article
- Characterization of heterozygosity-rich regions in Italian and worldwide goat breeds.Scientific reports · 2024Article
- Genetic diversity and historical demography of underutilised goat breeds in North-Western Europe.Scientific reports · 2023Article
- Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds.BMC genomics · 2023Article
- Selection, recombination and population history effects on runs of homozygosity (ROH) in wild red deer (Cervus elaphus).Heredity · 2023Article
- The demographic history of house mice (Mus musculus domesticus) in eastern North America.G3 (Bethesda, Md.) · 2023Article
- Analysis of runs of homozygosity of cattle living in different climate zones.Journal of animal science · 2023Article
- Identification of runs of homozygosity in Western honey bees (Ecology and evolution · 2023Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatterns of homozygosity can be influenced by several factors, such as demography, recombination, and selection. Using the goat SNP50 BeadChip, we genotyped 3171 goats belonging to 117 populations with a worldwide distribution. Our objectives were to characterize the number and length of runs of homozygosity (ROH) and to detect ROH hotspots in order to gain new insights into the consequences of neutral and selection processes on the genome-wide homozygosity patterns of goats.
resultsThe proportion of the goat genome covered by ROH is, in general, less than 15% with an inverse relationship between ROH length and frequency i.e. short ROH (< 3 Mb) are the most frequent ones. Our data also indicate that ~ 60% of the breeds display low F
conclusionsPatterns of homozygosity (average number of ROH of 77 and genome coverage of 248 Mb; F
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