Evidence map›Paper›PMID 30449277›Full record

ArticleGenetics, selection, evolution : GSE2018

Patterns of homozygosity in insular and continental goat breeds.

Taina F Cardoso, Marcel Amills, Francesca Bertolini, Max Rothschild, Gabriele Marras, Geert Boink, Jordi Jordana, Juan Capote, Sean Carolan, Jón H Hallsson and 4 more

Abstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

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0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Taina F CardosoDepartment of Animal Genetics, Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.
Marcel AmillsDepartment of Animal Genetics, Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain. marcel.amills@uab.cat.ORCID http://orcid.org/0000-0002-8999-0770
Francesca BertoliniDepartment of Animal Science, Iowa State University, Ames, IA, 50011-3150, USA.
Max RothschildDepartment of Animal Science, Iowa State University, Ames, IA, 50011-3150, USA.
Gabriele MarrasBioinformatics Core Facility, Fondazione Parco Tecnologico Padano, Loc. Cascina Codazza, 26900, Lodi, LO, Italy.
Geert BoinkStichting Zeldzame Huisdierrassen, De Drieslag 30, 8251 JZ, Dronten, The Netherlands.
Jordi JordanaDepartament de Ciència Animal i dels Aliments, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Juan CapoteInstituto Canario de Investigaciones Agrarias, 38108, La Laguna, Tenerife, Spain.
Sean CarolanThe Old Irish Goat Society, Mulranny, Co Mayo, Ireland.
Jón H HallssonFaculty of Land and Animal Resources, Agricultural University of Iceland, Reykjavík, Iceland.
Juha KantanenDepartment of Production Systems, Natural Resources Institute Finland, 31600, Jokioinen, Finland.
Agueda PonsUnitat de Races Autòctones, Servei de Millora Agrària i Pesquera (SEMILLA), 07198, Son Ferriol, Spain.
Johannes A LenstraFaculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. j.a.lenstra@uu.nl.
AdaptMap Consortium

Funding

Ministerio de Economía y Competitividad AGL2016-76108-R
6 · The paper itself

Abstract

backgroundGenetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds.

resultsAmong the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and F

conclusionsThese results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management.

Indexed as

BreedingHomozygotePolymorphism, Single NucleotideAnimalsEuropeGenetics, PopulationGenetic VariationGenomicsGenotypeGoatsIcelandIrelandMadagascarMediterranean IslandsMoroccoPopulation Density

Identifiers

PMID30449277
PMCPMC6241035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.