Evidence map›Paper›PMID 30448980›Full record

ReviewObesity surgery2019

Lithium Toxicity with Severe Bradycardia Post Sleeve Gastrectomy: a Case Report and Review of the Literature.

Arik Dahan, Daniel Porat, Carmil Azran, Yoni Mualem, Nasser Sakran, Subhi Abu-Abeid

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  9. Review
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  11. Review
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  15. Review
  16. Article
  17. Lithium toxicity following bariatric surgery.SAGE open medical case reports · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Arik DahanDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Beer-Sheva, Israel. arikd@bgu.ac.il.ORCID 0000-0002-3498-3514
Daniel PoratDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Beer-Sheva, Israel.
Carmil AzranClinical Pharmacy, Herzliya Medical Center, Herzliya, Israel.
Yoni MualemDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105, Beer-Sheva, Israel.
Nasser SakranDepartment of Surgery A, Emek Medical Center, Afula, Israel.
Subhi Abu-AbeidBariatric Surgery Unit, General Surgery Division, The Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Ben-Gurion University of the Negev · ILEmek Medical Center · ILHerzliya Medical Center · ILTel Aviv Sourasky Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lithium is one of the major treatment options in bipolar disorder. Bariatric surgery can significantly modify the oral bioavailability of drugs, and lithium is no exception; although in most cases drug absorption seems to decrease, in the case of lithium, toxicity is the risk. In this article, we describe a 61-year-old male patient presented with lithium toxicity, including newly diagnosed severe bradycardia requiring a permanent pacemaker, after undergoing sleeve gastrectomy. We discuss the mechanisms behind this case, provide potential solutions for clinicians treating bariatric patients with lithium, and review previous reports of lithium toxicity post bariatric surgery. Awareness of changes in drug absorption, particularly lithium, following bariatric surgery, is prudent and essential for optimal patient care. Close clinical and drug levels monitoring is strongly advised.

Indexed as

GastrectomyPostoperative ComplicationsAntimanic AgentsBipolar DisorderBradycardiaHumansLithium CompoundsMaleMiddle AgedAntimanic AgentsLithium CompoundsBariatric surgeryBipolar disorderBradycardiaDrug absorptionLithium toxicitySleeve gastrectomy

Identifiers

PMID30448980
OpenAlexW2900738288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.