Evidence map›Paper›PMID 30448921›Full record

ArticleJournal of molecular modeling2018

Probing the mechanism of SIRT1 activation by a 1,4-dihydropyridine.

Debashri Manna, Rajabrata Bhuyan, Rita Ghosh

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular modeling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Debashri MannaDepartment of Biochemistry and Biophysics, University of Kalyani, Nadia, West Bengal, 741235, India.
Rajabrata BhuyanDepartment of Biochemistry and Biophysics, University of Kalyani, Nadia, West Bengal, 741235, India.
Rita GhoshDepartment of Biochemistry and Biophysics, University of Kalyani, Nadia, West Bengal, 741235, India. rghosh_bcbp@klyuniv.ac.in.
University of Kalyani · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/BI/25/001/2006University of Kalyani M.S.No.Rev/1008 of 2017-18
6 · The paper itself

Abstract

The NAD

Indexed as

Molecular Docking SimulationThermodynamicsBinding SitesDihydropyridinesEnzyme ActivationEnzyme ActivatorsHumansMolecular StructureNADProtein BindingProtein DomainsSirtuin 1Substrate Specificity1,4-dihydropyridineDihydropyridinesEnzyme ActivatorsNADSIRT1 protein, humanSirtuin 11,4-DHPActivationDynamics and simulationp53SIRT1

Identifiers

PMID30448921
OpenAlexW2901843419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.