Evidence map›Paper›PMID 30448596›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2019

Pathology Characterization and Detection of Human Papillomavirus Type 16 in Rectal Squamous Cell Carcinomas.

Anna E Coghill, Andrew M Bellizzi, Charles F Lynch, Meredith S Shiels, Freda R Selk, Maura Gillison, Brenda Y Hernandez, Owen T M Chan, Eric A Engels

Open access · greenAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Anna E CoghillDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland. Electronic address: anna.coghill@moffitt.org.
Andrew M BellizziHolden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.
Charles F LynchHolden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa; Iowa Cancer Registry, University of Iowa, Iowa City, Iowa.
Meredith S ShielsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.
Freda R SelkIowa Cancer Registry, University of Iowa, Iowa City, Iowa.
Maura GillisonM.D. Anderson Cancer Center, Houston, Texas.
Brenda Y HernandezUniversity of Hawaii Cancer Center, Honolulu, Hawaii.
Owen T M ChanUniversity of Hawaii Cancer Center, Honolulu, Hawaii.
Eric A EngelsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.
University of Iowa · USDivision of Cancer Epidemiology and GeneticsCancer Center of Hawaii · USNational Cancer Institute · USThe University of Texas MD Anderson Cancer Center · USUniversity of Hawaiʻi at Mānoa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Mark E Burkard · 2000 to 2026
$70.0M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
Intramural NIH HHS Z99 CA999999NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Rectal squamous cell carcinoma (SCC) is a rare tumor with unresolved etiology. Human immunodeficiency virus-infected individuals and solid organ transplant recipients experience >30-fold and approximately 3-fold elevated rates of rectal SCC, respectively, suggesting immunosuppression plays a role.

Indexed as

AdenocarcinomaAnus NeoplasmsBiomarkersCarcinoma, Squamous CellCase-Control StudiesDNA-Binding ProteinsDNA, ViralHuman papillomavirus 16HumansIn Situ HybridizationKeratinsOncogene Proteins, ViralPapillomavirus InfectionsRectal NeoplasmsRepressor ProteinsTranscription FactorsBiomarkersCAM 5.2 antigenDNA-Binding ProteinsDNA, ViralE6 protein, HPV-33E6 protein, Human papillomavirus type 16E6 protein, Human papillomavirus type 18E6 protein, human papillomavirus type 45KeratinsOncogene Proteins, ViralRepressor ProteinsTP63 protein, humanTranscription FactorsTumor Suppressor ProteinsViral Envelope Proteins

Identifiers

PMID30448596
PMCPMC6520215
OpenAlexW2901750728

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.