Evidence map›Paper›PMID 30448017›Full record

ArticleDNA repair2019

Processing of N

Irina G Minko, Plamen P Christov, Liang Li, Michael P Stone, Amanda K McCullough, R Stephen Lloyd

Abstract read
In one paragraph

Article in DNA repair, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Research progress on the role of the NEIL family in cancer.Frontiers in cell and developmental biology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. HumanJournal of the American Chemical Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Irina G MinkoOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR 97239, United States.
Plamen P ChristovVanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Vanderbilt University, Nashville, TN 37235, United States.
Liang LiDepartment of Chemistry and Biochemistry, Vanderbilt-Ingram Cancer Center, Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, United States.
Michael P StoneDepartment of Chemistry and Biochemistry, Vanderbilt-Ingram Cancer Center, Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, United States.
Amanda K McCulloughOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR 97239, United States; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, United States.
R Stephen LloydOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR 97239, United States; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, United States; Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR 97239, United States. Electronic address: lloydst@ohsu.edu.
Oregon Health & Science University · USVanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
Synthetic Approaches to Carcinogen-Linked OligonucleotidesP01CA160032 · NCI · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2012 to 2022
$14.0M
TRAINING GRANTS IN ENVIROMENTAL TOXICOLOGYT32ES007020 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1985 to 2024
$13.1M
DNA Adduct-Induced MutagenesisR01CA055678 · NCI · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 1992 to 2016
$4.0M
DNA Adduct-Induced MutagenesisR01ES029357 · NIEHS · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2018 to 2022
$2.6M
ACQUISITION OF A 500 MHZ LC-NMR: PEPTIDE CHEMISTRYS10RR019022 · NCRR · VANDERBILT UNIVERSITY · PI RIZZO, CARMELO J · 2005 to 2005
$500k
The roles of BER and TLS in limiting aflatoxin-induced carcinogenesisR56ES027632 · NIEHS · OREGON HEALTH & SCIENCE UNIVERSITY · PI LLOYD, R. STEPHEN · 2017 to 2017
$308k
NCI NIH HHS P01 CA160032NCI NIH HHS P30 CA068485NCI NIH HHS P30 CA077598NCI NIH HHS R01 CA055678NCRR NIH HHS S10 RR019022NIEHS NIH HHS R01 ES029357NIEHS NIH HHS R56 ES027632
6 · The paper itself

Abstract

A variety of agents cause DNA base alkylation damage, including the known hepatocarcinogen aflatoxin B

Indexed as

AnimalsDNA AdductsDNA GlycosylasesMiceN-Glycosyl HydrolasesPyrimidinesDNA AdductsDNA GlycosylasesNEIL1 protein, humanNEIL3 protein, humanN-Glycosyl HydrolasespyrimidinePyrimidinesAflatoxinBase excision repairDNA alkylationNitrogen mustardRing-fragmented purines

Identifiers

PMID30448017
PMCPMC6588396
OpenAlexW2899911984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.