Evidence map›Paper›PMID 30447912›Full record

Trial reportBiological psychiatry2019

Early Parenting Intervention and Adverse Family Environments Affect Neural Function in Middle Childhood.

Johanna Bick, Erin N Palmwood, Lindsay Zajac, Robert Simons, Mary Dozier

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Biological psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Johanna BickDepartment of Psychology, University of Houston, Houston, Texas. Electronic address: jrbick@uh.edu.
Erin N PalmwoodDepartment of Psychological and Brain Sciences, University of Delaware, Newark, Delaware.
Lindsay ZajacDepartment of Psychological and Brain Sciences, University of Delaware, Newark, Delaware.
Robert SimonsDepartment of Psychological and Brain Sciences, University of Delaware, Newark, Delaware.
Mary DozierDepartment of Psychological and Brain Sciences, University of Delaware, Newark, Delaware.
University of Delaware · USUniversity of Houston · US

Funding

Specialized services for high-risk birth parentsR01MH074374 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY, TOTTENHAM, NIM · 2006 to 2023
$10.1M
SPECIALIZED MENTAL HEALTH SERVICES FOR FOSTER INFANTSR01MH052135 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY · 1996 to 2014
$6.7M
Early intervention for children adopted internationallyR01MH084135 · NIMH · UNIVERSITY OF DELAWARE · PI DOZIER, MARY · 2009 to 2013
$3.1M
NIMH NIH HHS R01 MH052135NIMH NIH HHS R01 MH074374NIMH NIH HHS R01 MH084135
6 · The paper itself

Abstract

backgroundGrowing work points to the negative impact of early adverse experiences on the developing brain. An outstanding question concerns the extent to which early intervention can normalize trajectories of brain development in at-risk children. We tested this within the context of a randomized clinical trial of an early parenting program, the Attachment and Biobehavioral Catch-up (ABC), delivered to parents and infants monitored for maltreatment by Child Protective Services.

methodsFamilies participated in the randomized clinical trial when children were 2.5 years of age or younger. Parenting and home adversity was measured at baseline. Children were followed longitudinally, and resting brain activity was measured electrophysiologically (n = 106) when children reached 8 years of age. Spectral power was quantified and compared across children assigned to the experimental intervention (ABC), a control intervention, and a low-risk comparison group (n = 76) recruited at the follow-up assessment.

resultsHigher early home adversity was associated with electrophysiological profiles indicative of cortical delays/immaturity in middle childhood, based on relatively greater power in lower frequency bands (theta, 4-6 Hz, and low alpha, 6-9 Hz) and lower power in a higher frequency band (high alpha, 9-12 Hz). Children assigned to ABC showed relatively greater high-frequency power (beta, 12-20 Hz) than children assigned to the control intervention. Beta power in the ABC did not differ from that of the low-risk comparison group.

conclusionsMaltreatment risk and home adversity can affect indicators of middle childhood brain maturation. Early parenting programs can support more normative patterns of neural function during middle childhood.

Indexed as

FamilyFamily TherapyBrainBrain WavesChildChild AbuseChild, PreschoolElectroencephalographyEnvironmentFemaleHumansLongitudinal StudiesMaleParentingBrain maturationChildhood maltreatmentEarly adversityEarly interventionParentingResting EEG

Identifiers

PMID30447912
PMCPMC6373871
OpenAlexW2895284474

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.