Evidence map›Paper›PMID 30447306›Full record

ArticleRespiratory physiology & neurobiology2019

Increased tongue use enhances 5-HT

Rajat K Das, Kate B Herr, Anjum Parkar, Leszek Kubin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory physiology & neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rajat K DasDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Kate B HerrDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Anjum ParkarDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Leszek KubinDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address: lkubin@vet.upenn.edu.
University of Pennsylvania · US

Funding

Upper airway control during disrupted and misaligned sleepR01HL116508 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KUBIN, LESZEK K · 2013 to 2015
$1.2M
NHLBI NIH HHS R01 HL116508
6 · The paper itself

Abstract

Hypoglossal (XII) motoneurons are activated by type 2 receptors for serotonin (5-HT). This activation is especially strong during wakefulness which facilitates diverse motor functions of the tongue, including the maintenance of upper airway patency in obstructive sleep apnea (OSA) patients. We tested whether 5-HT

Indexed as

Analysis of VarianceAnimalsDiaphragmDrinkingElectromyographyGene Expression RegulationHypoglossal NerveLocomotionMaleMedulla OblongataMotor NeuronsProto-Oncogene Proteins c-fosRatsRats, Sprague-DawleyReceptor, Serotonin, 5-HT2CTongueProto-Oncogene Proteins c-fosReceptor, Serotonin, 5-HT2CDrinkingGroomingMotor rehabilitationObstructive sleep apneaPlasticitySerotonin receptorsUse-dependence

Identifiers

PMID30447306
PMCPMC6326864
OpenAlexW2900531634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.