ArticleVirus research2019
Full genome characterization of two novel Alpha-coronavirus species from Italian bats.
Article in Virus research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Pooled it
- Coronavirus diversity and SARS-CoV-2 exposure at the wildlife-human interface in Northern Italy.Virology journal · 2026Article
- Identification and characterization of novel bat coronaviruses in Spain.PLoS pathogens · 2025Article
- Presence ofViruses · 2024Article
- Comparison of antiviral responses in two bat species reveals conserved and divergent innate immune pathways.iScience · 2023Article
- In Vitro Replication of Swine Hepatitis E Virus (HEV): Production of Cell-Adapted Strains.Animals : an open access journal from MDPI · 2023Article
- Review
- Mass spectrometry applied to diagnosis, prognosis, and therapeutic targets identification for the novel coronavirus SARS-CoV-2: A review.Analytica chimica acta · 2022Review
- A study of viral pathogens in bat species in the Iberian Peninsula: identification of new coronavirus genetic variants.International journal of veterinary science and medicine · 2022Article
- Discovery of two novelFrontiers in microbiology · 2022Article
- Exploring the diversity of coronavirus in sewage during COVID-19 pandemic: Don't miss the forest for the trees.The Science of the total environment · 2021Article
- Metagenomic Analysis Reveals Previously Undescribed Bat Coronavirus Strains in Eswatini.EcoHealth · 2021Article
- Update on Potentially Zoonotic Viruses of European Bats.Vaccines · 2021Review
- Targeting novel structural and functional features of coronavirus protease nsp5 (3CLThe Journal of general virology · 2021Review
- Bats, Pathogens, and Species Richness.Pathogens (Basel, Switzerland) · 2021Article
- The taxonomy, host range and pathogenicity of coronaviruses and other viruses in theAnimal diseases · 2021Review
- Gene Presence/Absence Variation analysis of coronavirus family displays its pan-genomic diversity.International journal of biological sciences · 2021Article
- Comparative analysis of the genome structure and organization of the Middle East respiratory syndrome coronavirus (MERS-CoV) 2012 to 2019 revealing evidence for virus strain barcoding, zoonotic transmission, and selection pressure.Reviews in medical virology · 2021Review
- Review
- Long-term surveillance of bat coronaviruses in Korea: Diversity and distribution pattern.Transboundary and emerging diseases · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronaviruses (CoVs) have been detected worldwide in several bat species, which are considered the main reservoir. The attention to the high diversity of CoVs hosted by bats has increased during the last decade due to the high number of human infections caused by two zoonotic Beta-CoVs, SARS-CoV and MERS-CoV, that cause several respiratory diseases. Among coronaviruses, two Alpha-CoV strains (HuCoV-229E and HuCoV-NL63) cause mild respiratory disease that can change to severe disease in children, elderly and individuals affected by illnesses. Phylogenetic analysis conducted on bat Alpha-CoV strains revealed their evolutive correlation to human strains, suggesting their origin in bats. The genome of CoVs is characterized by a high frequency of mutations and recombination events, increasing their ability to switch hosts and their zoonotic potential. In this study, three strains of Alpha-CoV genera detected in Italian bats (Pipistrellus kuhlii) were fully sequenced by Next Generation Sequencing (NGS) and characterized. The complete genome analysis showed the correlation of the Italians strains with a Chinese strain detected in 2013 and, based on CoV molecular species demarcation, two new Alpha-CoV species were established. The analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) showed the correlation of the Italian strains with CoVs that was only detected in the bat Pipistrellus genera (Pipistrellus kuhlii and Pipistrellus Pipistrellus) in European countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.