Evidence map›Paper›PMID 30447075›Full record

ArticleClinical cardiology2019

Bioelectrical impedance analysis of body composition and survival in patients with heart failure.

Elizabeth Thomas, Pritha P Gupta, Gregg C Fonarow, Tamara B Horwich

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  13. Obesity paradox and heart failure.Eating and weight disorders : EWD · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elizabeth ThomasOxford University, Pembroke College, Oxford, UK.
Pritha P GuptaDivision of Cardiology, David Geffen School of Medicine at UCLA, California, Los Angeles.
Gregg C FonarowDivision of Cardiology, David Geffen School of Medicine at UCLA, California, Los Angeles.ORCID https://orcid.org/0000-0002-3192-8093
Tamara B HorwichDivision of Cardiology, David Geffen School of Medicine at UCLA, California, Los Angeles.ORCID https://orcid.org/0000-0002-3208-1023
University of California, Los Angeles · USUniversity of North Carolina at Pembroke · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have shown that higher body mass index (BMI) is associated with improved prognosis in heart failure (HF), and this is often termed the obesity paradox. HYPOTHESIS: Analysis of body composition may reveal that muscle mass rather than adipose tissue accounts for the obesity paradox.

methodsBioelectrical impedance analysis of body composition in 359 outpatients with HF was performed using an In Body 520 body composition scale (Biospace Inc., California). Body fat and lean mass were indexed by height (m

resultsThe mean age of patients studied was 56 ± 14; mean left ventricular ejection fraction was 38 ± 16%. Patients with higher indexed body fat mass had improved 5-year survival over patients with lower indexed body fat mass (90.2% vs 80.1%, P = 0.008). There was also improved survival in patients with high vs low indexed lean body mass (89.3% vs 80.9%, P = 0.036). On multivariable analysis, higher indexed body fat mass, but not lean body mass, was independently associated with improved survival (HR 0.89, per kg/m

conclusionsOur data suggest that higher fat mass-and to a lesser extent higher lean mass-is associated with improved outcomes in HF. Further investigations of specific components of body composition and outcomes in HF are warranted.

Indexed as

Body CompositionComorbidityElectric ImpedanceFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedObesityPrognosisRetrospective StudiesStroke VolumeSurvival RateTime FactorsUnited Statesbody compositionheart failureobesity paradoxoutcomes

Identifiers

PMID30447075
PMCPMC6436517
OpenAlexW2901212211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.