Evidence map›Paper›PMID 30446926›Full record

ArticleInflammopharmacology2019

Plantago squarrosa Murray extracts inhibit the growth of some bacterial triggers of autoimmune diseases: GC-MS analysis of an inhibitory extract.

Elsayed Omer, Abdelsamed I Elshamy, Mahmoud Nassar, Joseph Shalom, Alan White, Ian E Cock

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Chinese herbal medicines · 2026
    Review
  2. Article
  3. Review
  4. Plants (Basel, Switzerland) · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elsayed OmerMedicinal and Aromatic Plants Research Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Abdelsamed I ElshamyChemistry of Natural Compounds Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Mahmoud NassarChemistry of Natural Compounds Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Joseph ShalomSchool of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, QLD, 4111, Australia.
Alan WhiteSchool of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, QLD, 4111, Australia.
Ian E CockSchool of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, QLD, 4111, Australia. I.Cock@griffith.edu.au.ORCID http://orcid.org/0000-0002-8732-8513
Griffith University · AUNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosing spondylitis, multiple sclerosis, rheumatoid arthritis and rheumatic fever are autoimmune inflammatory diseases that may be triggered in genetically susceptible individuals by specific bacterial pathogens. Inhibiting the growth of these bacteria with high antioxidant plant extracts may inhibit the aetiology of these diseases, as well as inhibiting the later phase symptoms. P. squarrosa extracts were analysed for antioxidant activity using a DPPH free radical scavenging assay. Bacterial growth inhibitory activity was evaluated using disc diffusion assays and the activity was quantified by MIC determination. The extracts were screened for toxicity by A. franciscana nauplii assays. The most potent antibacterial extract (ethyl acetate) was analysed by GC-MS headspace profile analysis and compounds were identified with reference to a phytochemical database. All extracts displayed strong DPPH radical scavenging activity. The ethyl acetate extract was particularly potent (IC

Indexed as

Anti-Bacterial AgentsAntioxidantsAutoimmune DiseasesBacteriaGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsPlantagoPlant ExtractsPlant LeavesAnti-Bacterial AgentsAntioxidantsPlant ExtractsAcinetobacter baylyiAnkylosing spondylitisMolecular mimicryMultiple sclerosisProteus mirabilisPseudomonas aeruginosaRheumatoid arthritis

Identifiers

PMID30446926
OpenAlexW2901847656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.