Evidence map›Paper›PMID 30446890›Full record

ArticleJournal of industrial microbiology & biotechnology2019

Metabolic engineering of Corynebacterium glutamicum for improved L-arginine synthesis by enhancing NADPH supply.

Milin Zhan, Baojun Kan, Jinjun Dong, Guochao Xu, Ruizhi Han, Ye Ni

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. Optimizing L-Tryptophan Production inJournal of microbiology and biotechnology · 2025
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  4. Response surface-based media optimization for astaxanthin production inFrontiers in bioengineering and biotechnology · 2025
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  5. Article
  6. Utilization of orange peel waste for sustainable amino acid production byFrontiers in bioengineering and biotechnology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Production of l-glutamate family amino acids inSynthetic and systems biotechnology · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Improvement of l-Leucine Production inInternational journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Milin ZhanKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Baojun KanKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Jinjun DongKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Guochao XuKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Ruizhi HanKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Ye NiKey Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, Jiangsu, China. yni@jiangnan.edu.cn.ORCID http://orcid.org/0000-0003-4887-7517
Jiangnan University · CN

Funding

National First-class Discipline Program of Light Industry Technology and Engineering LITE2018-07National Natural Science Foundation of China 31601463Six talent peaks project of Jiangsu Province 2015-SWYY-008
6 · The paper itself

Abstract

Corynebacterium glutamicum SNK 118 was metabolically engineered with improved L-arginine titer. Considering the crucial role of NADPH level in L-arginine production, pntAB (membrane-bound transhydrogenase) and ppnK (NAD

Indexed as

Metabolic EngineeringArginineBacterial ProteinsBatch Cell Culture TechniquesBioreactorsCorynebacterium glutamicumFermentationGene Expression Regulation, BacterialGlucoseIndustrial MicrobiologyNADPNADP TranshydrogenasesRepressor ProteinsArginineArgR protein, BacteriaBacterial ProteinsGlucoseNADPNADP TranshydrogenasesRepressor ProteinsCorynebacterium glutamicumL-ArginineNAD+ kinaseNADPHNADP+ transhydrogenase

Identifiers

PMID30446890
OpenAlexW2901084012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.