Evidence map›Paper›PMID 30446826›Full record

Trial reportJournal of anesthesia2019

Three versus five lumbar paravertebral injections for inguinal hernia repair in the elderly: a randomized double-blind clinical trial.

Zoher Naja, Saleh Kanawati, Ziad El Khatib, Fouad Ziade, Rakan Nasreddine, Ahmad Salah Naja

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of anesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02537860 (Paravertebral Block for Inguinal Hernia Repair in Elderly), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02537860 nacompletednot on this map

Paravertebral Block for Inguinal Hernia Repair in Elderly: Randomized Double-blinded Clinical Trial

TypeinterventionalSponsorMakassed General HospitalRan2015 to 2017Enrolled200ConditionsInguinal Hernia RepairArmsParavertebral block injections from T12 to L2, Placebo at T11 and L3, Paravertebral block injections between T11 and L3, Herniorrhaphy, Intravenous (IV) fentanyl
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zoher NajaAnesthesia and Pain Management Department, Makassed General Hospital, P.O. Box: 11-6301, Riad EI-Solh, Beirut, 11072210, Lebanon. zouhnaja@yahoo.com.ORCID http://orcid.org/0000-0003-4647-1839
Saleh KanawatiAnesthesia and Pain Management Department, Makassed General Hospital, P.O. Box: 11-6301, Riad EI-Solh, Beirut, 11072210, Lebanon.
Ziad El KhatibSurgery Department, Makassed General Hospital, Beirut, Lebanon.
Fouad ZiadeFaculty of Public Health, Lebanese University, Beirut, Lebanon.
Rakan NasreddineAmerican University of Beirut Medical Center, Beirut, Lebanon.
Ahmad Salah NajaAmerican University of Beirut Medical Center, Beirut, Lebanon.
Makassed General Hospital · LBAmerican University of Beirut Medical Center · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of the study was to compare three nerve stimulator-guided paravertebral injections versus five injections for elderly patients undergoing inguinal hernia repair in terms of the amount of intraoperative fentanyl and propofol consumption and conversion to general anesthesia. The secondary objective was postoperative pain.

methodsA prospective, randomized, double-blind clinical trial was performed. 200 elderly patients undergoing unilateral herniorrhaphy were randomized into two groups. Group III received three PVB injections from T

resultsThe mean intraoperative fentanyl and propofol consumption were significantly lower in group V (4.9 ± 7.2 µg versus 20.0 ± 12.9 µg and 5.7 ± 11.6 mg versus 34.6 ± 22.9 mg, respectively, p value < 0.0001). Five patients (5.0%) in group III had failed block and were converted to general anesthesia (p value = 0.024). Group V had significantly lower pain scores compared to group III during the first three postoperative days (p value < 0.0001).

conclusionThe five PVB injection technique is more suitable as a sole anesthetic technique for elderly patients undergoing herniorrhaphy, since it required less intraoperative supplemental analgesia and provided lower postoperative pain scores compared to the three PVB injection technique.

trial registrationClinicaltrials.gov identifier: NCT02537860.

Indexed as

AgedAnesthesia, GeneralAnestheticsDouble-Blind MethodFemaleFentanylHernia, InguinalHerniorrhaphyHumansMaleMiddle AgedNerve BlockPostoperative PainPropofolProspective StudiesAnestheticsFentanylPropofolGeriatric anesthesiaNerve blockPostoperative pain

Identifiers

PMID30446826
OpenAlexW2901847654

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.