Evidence map›Paper›PMID 30446793›Full record

ReviewTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2019

Prospects of pan-genomics in barley.

Cécile Monat, Mona Schreiber, Nils Stein, Martin Mascher

Abstract readReview
PubMed Publisher
In one paragraph

Review in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in plant science · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Building pan-genome infrastructures for crop plants and their use in association genetics.DNA research : an international journal for rapid publication of reports on genes and genomes · 2021
    Review
  15. Article
  16. Article
  17. Identifying barley pan-genome sequence anchors using genetic mapping and machine learning.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020
    Article
  18. Review
  19. Fine mapping of leaf rust resistance gene Rph13 from wild barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Cécile MonatLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Corrensstraße 3, 06466, Seeland, Germany.
Mona SchreiberLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Corrensstraße 3, 06466, Seeland, Germany.
Nils SteinLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Corrensstraße 3, 06466, Seeland, Germany.
Martin MascherLeibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Corrensstraße 3, 06466, Seeland, Germany. mascher@ipk-gatersleben.de.ORCID http://orcid.org/0000-0001-6373-6013
Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DEGerman Centre for Integrative Biodiversity Research · DE

Funding

Bundesministerium für Bildung und Forschung 031B0190ALeibniz-Gemeinschaft SAW-2015-IPK-1
6 · The paper itself

Abstract

The concept of a pan-genome refers to intraspecific diversity in genome content and structure, encompassing both genes and intergenic space. Pan-genomic studies employ a combination of de novo sequence assembly and reference-based alignment to discover and genotype structural variants. The large size and complex structure of Triticeae genomes were for a long time an obstacle for genomic research in barley and its relatives. Now that a reference genome is available, computational pipelines for high-quality sequence assembly are in place, and sequence costs continue to drop, investigations into the structural diversity of the barley genome seem within reach. Here, we review the recent progress on pan-genomics in the model grass Brachypodium distachyon, and the cereal crops rice and maize, and devise a multi-tiered strategy for a pan-genome project in barley. Our design involves: (1) the construction of high-quality de novo sequence assemblies for a small core set of representative genotypes, (2) short-read sequencing of a large diversity panel of genebank accessions to medium coverage and (3) the use of complementary methods such as chromosome-conformation capture sequencing and k-mer-based association genetics. The in silico representation of the barley pan-genome may inform about the mechanisms of structural genome evolution in the Triticeae and supplement quantitative genetics models of crop performance for better accuracy and predictive ability.

Indexed as

BrachypodiumCosts and Cost AnalysisGenome, PlantGenomicsHordeumOryza

Identifiers

PMID30446793
OpenAlexW2901148595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.