Evidence map›Paper›PMID 30446721›Full record

ArticleScientific reports2018

Low-level light therapy reduces platelet destruction during extracorporeal circulation.

Anna Drohomirecka, Alicja Iwaszko, Tomasz Walski, Aleksandra Pliszczak-Król, Grzegorz Wąż, Stanisław Graczyk, Katarzyna Gałecka, Albert Czerski, Jolanta Bujok, Małgorzata Komorowska

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Platelet Storage-Problems, Improvements, and New Perspectives.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Anna DrohomireckaDepartment of Heart Failure and Transplantology, Institute of Cardiology, Warsaw, Poland.
Alicja IwaszkoDepartment of Immunology, Pathophysiology and Veterinary Prevention, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Tomasz WalskiRegional Specialist Hospital in Wrocław, Research and Development Centre, Wrocław, Poland.ORCID http://orcid.org/0000-0003-2219-817X
Aleksandra Pliszczak-KrólDepartment of Immunology, Pathophysiology and Veterinary Prevention, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Grzegorz Wąż"Medinet" Lower Silesian Centre for Heart Diseases, Wrocław, Poland.
Stanisław GraczykDepartment of Immunology, Pathophysiology and Veterinary Prevention, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Katarzyna GałeckaRegional Specialist Hospital in Wrocław, Research and Development Centre, Wrocław, Poland.
Albert CzerskiDepartment of Animal Physiology and Biostructure, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Jolanta BujokRegional Specialist Hospital in Wrocław, Research and Development Centre, Wrocław, Poland. jolanta.bujok@upwr.edu.pl.
Małgorzata KomorowskaRegional Specialist Hospital in Wrocław, Research and Development Centre, Wrocław, Poland.
Wrocław University of Environmental and Life Sciences · PLWrocław University of Science and Technology · PLInstitute of Cardiology · PLSilesian Center for Heart Disease · PLUniversity of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal circulation causes many deleterious effects on blood cells. Low-level light therapy (LLLT) in the red/near-infrared spectral range is known for its cytoprotective properties but its use during cardiopulmonary bypass (CPB) has not yet been studied. We aimed to assess whether LLLT protects platelets during CPB. 24 pigs were connected to 1-hour-CPB and observed for the next 23 hours. In 12 animals, blood circulating through the oxygenator was treated with LLLT. Platelet count and function were monitored throughout the experiment. The decrease in platelet count was greater in the control group, especially during CPB and after 24 hours. In LLLT group CD62P expression remained quite stable up to the 12

Indexed as

AnimalsBlood PlateletsCardiopulmonary BypassExtracorporeal CirculationHumansLow-Level Light TherapyPlatelet AggregationPlatelet CountP-SelectinSwineThrombocytopeniaP-Selectin

Identifiers

PMID30446721
PMCPMC6240032
OpenAlexW2900835526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.