Evidence map›Paper›PMID 30446530›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults.

Jaime J Castrellon, Kendra L Seaman, Jennifer L Crawford, Jacob S Young, Christopher T Smith, Linh C Dang, Ming Hsu, Ronald L Cowan, David H Zald, Gregory R Samanez-Larkin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. The Genoeconomics of Impulsive Intertemporal Choice: A Critical Review.Journal of the experimental analysis of behavior · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Which came first: Cannabis use or deficits in impulse control?Progress in neuro-psychopharmacology & biological psychiatry · 2021
    Review
  11. Noradrenergic correlates of chronic cocaine craving: neuromelanin and functional brain imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  12. Review
  13. Article
  14. Risky decision-making predicts dopamine release dynamics in nucleus accumbens shell.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jaime J CastrellonDepartment of Psychology and Neuroscience, jaime.castrellon@duke.edu.ORCID 0000-0001-5834-7101
Kendra L SeamanCenter for Cognitive Neuroscience.ORCID 0000-0003-3008-923X
Jennifer L CrawfordDepartment of Psychology, Yale University, New Haven, Connecticut 06511.
Jacob S YoungDepartment of Psychology, Vanderbilt University, Nashville, Tennessee 37240.
Christopher T SmithDepartment of Psychology, Vanderbilt University, Nashville, Tennessee 37240.ORCID 0000-0002-8212-7886
Linh C DangDepartment of Psychology, Vanderbilt University, Nashville, Tennessee 37240.ORCID 0000-0001-6669-0495
Ming HsuHaas School of Business, University of California Berkeley, Berkeley, California 94720.ORCID 0000-0001-7195-3579
Ronald L CowanDepartment of Psychology, Vanderbilt University, Nashville, Tennessee 37240.
David H ZaldDepartment of Psychology, Vanderbilt University, Nashville, Tennessee 37240.ORCID 0000-0002-1229-2923
Gregory R Samanez-LarkinDepartment of Psychology and Neuroscience.ORCID 0000-0001-7846-3804
Vanderbilt University · USDuke University · USHôpital du Valais · CHUniversity of California, Berkeley · USYale University · US

Funding

Program Development (Pilot)P30AG012839 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI Magali Barbieri · 1999 to 2026
$18.6M
Dopaminergic Modulation of Subjective Valuation across AdulthoodR01AG044838 · NIA · VANDERBILT UNIVERSITY · PI ZALD, DAVID HAROLD · 2012 to 2014
$1.6M
Neurobiological Substrates of Social Behavior: A Neuroeconomic FrameworkR01MH098023 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HSU, MING · 2013 to 2017
$1.5M
Neuromodulation of Motivated Cognition and Decision Making Across AdulthoodR00AG042596 · NIA · YALE UNIVERSITY · PI SAMANEZ LARKIN, GREGORY R · 2014 to 2016
$730k
CRCNS: Neurocomputational substrates of monetary exchangeR01DA043196 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI HSU, MING · 2016 to 2018
$474k
Dopamine Influences on Self-Regulation and ImpulsivityR21DA033611 · NIDA · VANDERBILT UNIVERSITY · PI ZALD, DAVID HAROLD · 2011 to 2012
$367k
NIA NIH HHS R00 AG042596NIA NIH HHS R01 AG044838NIDA NIH HHS R21 DA033611
6 · The paper itself

Abstract

Some people are more willing to make immediate, risky, or costly reward-focused choices than others, which has been hypothesized to be associated with individual differences in dopamine (DA) function. In two studies using PET imaging, one empirical (Study 1:

Indexed as

Delay DiscountingRewardAdolescentAdultAgedAged, 80 and overAgingBehavior, AddictiveBrainBrain MappingDopamineFemaleHumansIndividualityMaleMental DisordersDopamineDRD2 protein, humanReceptors, Dopamine D2decision makingdelay discountingdopamineeffortPETprobability

Identifiers

PMID30446530
PMCPMC6325254
OpenAlexW2886965347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.