Evidence map›Paper›PMID 30446529›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity.

Rhona McGonigal, Jennifer A Barrie, Denggao Yao, Mark McLaughlin, Madeleine E Cunningham, Edward G Rowan, Hugh J Willison

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

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  10. Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rhona McGonigalUniversity of Glasgow, Institute of Infection, Immunity and Inflammation Glasgow G12 8TA, United Kingdom.ORCID 0000-0001-9571-2526
Jennifer A BarrieUniversity of Glasgow, Institute of Infection, Immunity and Inflammation Glasgow G12 8TA, United Kingdom.
Denggao YaoUniversity of Glasgow, Institute of Infection, Immunity and Inflammation Glasgow G12 8TA, United Kingdom.
Mark McLaughlinUniversity of Glasgow, School of Veterinary Biosciences, Glasgow G61 1QH, United Kingdom, and.
Madeleine E CunninghamUniversity of Glasgow, Institute of Infection, Immunity and Inflammation Glasgow G12 8TA, United Kingdom.ORCID 0000-0002-7545-6868
Edward G RowanUniversity of Strathclyde, Strathclyde Institute of Pharmacy and Biochemical Sciences, Glasgow G4 0RE, United Kingdom.
Hugh J WillisonUniversity of Glasgow, Institute of Infection, Immunity and Inflammation Glasgow G12 8TA, United Kingdom, Hugh.willison@glasgow.ac.uk.ORCID 0000-0002-5997-1683
Wellcome Centre for Molecular Parasitology · GBUniversity of Glasgow · GBUniversity of Strathclyde · GB

Funding

Wellcome Trust 202789/Z/16/Z
6 · The paper itself

Abstract

Sulfatides and gangliosides are raft-associated glycolipids essential for maintaining myelinated nerve integrity. Mice deficient in sulfatide (cerebroside sulfotransferase knock-out,

Indexed as

AnimalsAxonsCell Adhesion MoleculesFemaleGangliosidesGenotypeLife ExpectancyMaleMiceMice, Inbred C57BLMice, KnockoutMyelin-Associated GlycoproteinMyelin SheathN-AcetylgalactosaminyltransferasesNerve Growth FactorsNeurogliaCell Adhesion Moleculesgalactosylceramide sulfotransferaseGalNT7 protein, mouseGangliosidesMag protein, mouseMyelin-Associated GlycoproteinN-AcetylgalactosaminyltransferasesNerve Growth FactorsNfasc protein, mouseSulfoglycosphingolipidsSulfotransferasesaxo–glial integritygangliosideMAGNF155node of Ranviersulfatide

Identifiers

PMID30446529
PMCPMC6325269
OpenAlexW2901524940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.